Sort   by:  
 Page size 
ProteomicsHRD1-ERAD controls production of the hepatokine FGF21 through CREBH polyubiquitination
As a ubiquitin ligase, HRD1 may regulate FGF21 expression through targeting protein degradation. We then aimed to identify proteins whose expressions are altered at post-transcriptional levels in HRD1 LKO mouse liver
ORGANISM(S): Mus Musculus 
2021-12-14 | PXD030410 |
ProteomicsER -associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes
Mass spectrometry characterization of the proteins in complex with endogenous HRD1 yielded a total of 347 proteins from three independent experiments
ORGANISM(S): Homo Sapiens 
2018-04-04 | PXD009402 |
TranscriptomicsIRE1alpha is an endogenous substrate of endoplasmic reticulum-associated degradation
Endoplasmic reticulum-associated degradation (ERAD) represents a principle quality control (QC) mechanism to clear misfolded proteins in the ER; however, its physiological significance and the nature of endogenous ERAD substrates remain largely unknown. Here we discover that IRE1alpha, the sensor of...
ORGANISM(S): Mus musculus 
2015-11-04 | E-GEOD-70563 | biostudies-arrayexpress
Sort   by:  
 Page size