Sort   by:  
 Page size 
TranscriptomicsApplication of SNP microarrays to the genome-wide analysis of chromosomal instability in premalignant airway lesions
Chromosomal instability is central to the process of carcinogenesis. The detection of somatic chromosomal alterations in small premalignant lesions genome-wide remains challenging since sample heterogeneity dilutes the aberrant cell information. We introduced an analytic metric termed "delta-θ&...
ORGANISM(S): Homo sapiens 
2014-03-07 | E-GEOD-43168 | biostudies-arrayexpress
TranscriptomicsDifferential Gene Regulation during murine in vivo heart ischemia comparing wildtype and Per2 deficient mice
Disruption of peripheral circadian rhyme pathways dominantly leads to metabolic disorders. Studies on circadian rhythm proteins in the heart indicated a role for Clock or Per2 in cardiac metabolism. In fact, Per2-/- mice have larger infarct sizes with a deficient lactate production during myocardial...
ORGANISM(S): Mus musculus 
2013-08-21 | E-GEOD-45818 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiles of human primary alveolar type II (ATII) cells and macrophages (AMs) after influenza virus infection
Abnormal function of genes is at the root of most cancers, but heritable cancer syndromes account for a very small minority of all tumors in humans and domestic animals. The majority of cancers are “sporadic,” that is, they are not heritable in the strictest sense. Instead, sporadic cancers occur du...
ORGANISM(S): Homo sapiens 
2012-07-11 | E-GEOD-30723 | biostudies-arrayexpress
TranscriptomicsEarliest Changes in the Left Ventricular Transcriptome Post-Myocardial Infarction
We report a genome-wide survey of early responses of the mouse heart transcriptome to acute myocardial infarction (AMI). For three regions of the left ventricle (LV), namely ischemic/infarcted tissue (IF), the surviving LV free wall (FW) and the interventricular septum (IVS), 36,899 transcripts were...
ORGANISM(S): Mus musculus 
2006-07-13 | E-GEOD-4648 | biostudies-arrayexpress
Sort   by:  
 Page size