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TranscriptomicsThe conserved 3’ UTR-derived small RNA NarS mediates mRNA crossregulation during nitrate respiration
In pursuit of a biological role of Salmonella 3' UTR derived sRNA NarS ,we sought to determine potential target mRNAs of NarS under anaerobic conditions. To this end, we compared gene expression in NarS-deficient and NarS overexpression (from plasmid pPL-NarS) strains following a 30-minute anaerobic...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2019-08-22 | E-MTAB-8244 | biostudies-arrayexpress
TranscriptomicsComparative miRNA Expression Profiles in Individuals with Latent and Active Tuberculosis
To study the role of miRNAs in the transition from latent to active TB and to discover candidate biomarkers that may help predict TB progression, we have employed miRNA microarray expression profiling as a discovery platform to probe the transcriptome of peripheral blood mononuclear cells (PBMCs) wi...
ORGANISM(S): Homo sapiens 
2011-05-10 | E-GEOD-29190 | biostudies-arrayexpress
TranscriptomicseQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors
Motivation: Identification of eQTL, the genetic loci that contribute to heritable variation in gene expression, can be obstructed by factors that produce variation in expression profiles if these factors are unmeasured or hidden from direct analysis. Methods: We have developed a method for Hidden Ex...
ORGANISM(S): Homo sapiens 
2014-01-07 | E-GEOD-40364 | biostudies-arrayexpress
MetabolomicsThe impact of slyA on cell metabolism of Salmonella Typhimurium: a joint study of transcriptomics and metabolomics

Salmonella Typhimurium (S. typhimurium), a gram-negative foodborne pathogen, is the leading cause of Salmonella food poisoning in humans. slyA has been demonstrated to be a critical transcriptional regulator in S. typhimurium, enabling the pathogen to survive in host cells by modulating the expre...

2020-10-11 | MTBLS1858 | MetaboLights
UnknownA PD-L1-Based Cancer Vaccine Elicits Antitumor Immunity in a Mouse Melanoma Model.
Not available
S-EPMC6667823 | biostudies-literature
UnknownBlockading a new NSCLC immunosuppressive target by pluripotent autologous tumor vaccines magnifies sequential immunotherapy.
Not available
S-EPMC8843980 | biostudies-literature
UnknownGain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia.
Not available
S-EPMC2538883 | biostudies-literature
UnknownThe deficiency of Maged1 attenuates Parkinson's disease progression in mice.
Not available
S-EPMC9921624 | biostudies-literature
TranscriptomicsExpression profiling of BMP9-stimulated mesenchymal stem cells
To identify potential target genes regulated by BMP9 in MSCs, we used microarray to profile expression patterns of BMP9- vs. GFP-stimulated MSCs. Subconfluent mouse C3H10T1/2 cells were transduced with adenoviral vector expressing BMP9 or GFP for 30h. Total RNA was isolated for microarray analysis u...
ORGANISM(S): Mus musculus 
2013-07-16 | E-GEOD-48882 | biostudies-arrayexpress
UnknownThe utilization of aerosol therapy in mechanical ventilation patients: a prospective multicenter observational cohort study and a review of the current evidence.
Not available
S-EPMC7575997 | biostudies-literature
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