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TranscriptomicsTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
We sequenced mRNA from individual stormal cells (Macrophages, Monocytes, and Neutrophils) and tumor epithelial cells from KrasG12dD; p53-/- murine lung cancer model and WT control mouse to compare gene expressio profiles of lung cancer stroma and tumor cells to their counterparts of WT lugns. The tu...
ORGANISM(S): Mus musculus 
2015-03-06 | E-GEOD-59831 | biostudies-arrayexpress
TranscriptomicsExpression data of Sorted CD11b+Gr1+ cells from mice with or without LLC tumor challenging
We sought to identify genes that are differentially regulated in CD11b+Gr1+ cells after tumor challenging. Mice were challenged with LLC-RFP cells (5×10^6 cells, subcutaneous injection) for 9 days. Single cell suspensions were prepared from lungs of both tumor challenged and control wild type mice a...
ORGANISM(S): Mus musculus 
2012-01-01 | E-GEOD-20180 | biostudies-arrayexpress
TranscriptomicsSuppression of miRNA-708 by polycomb group promotes metastases by calcium-induced cell migration
The progression of cancer to metastatic disease is a major cause of death. We identified miR-708 being transcriptionally repressed by polycomb repressor complex (PRC2)-induced H3-K27 trimethylation in metastatic breast cancer. miR-708 targets the endoplasmic reticulum protein neuronatin (Nnat) to d...
ORGANISM(S): Homo sapiens 
2013-11-15 | E-GEOD-42313 | biostudies-arrayexpress
TranscriptomicsDifferential expression of GFP+ and RFP+ TriPyMT cells
Tri-PyMT cell is a breast tumor cell line established from Tri-PyMT (MMTV-PyMT/fsp1-Cre/Rosa26-RGFP) primary breast tumors. The cells switch from RFP+ to GFP+ during epithelial to mesenchymal transition (EMT). Differential expressed genes between EMT and non-EMT tumor cells will reveal interesting t...
ORGANISM(S): Mus musculus 
2015-09-01 | E-GEOD-72480 | biostudies-arrayexpress
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