Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Hyejin Choi
PROVIDER: E-GEOD-59831 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Cell reports 20150219 7
Emerging studies have begun to demonstrate that reprogrammed stromal cells play pivotal roles in tumor growth, metastasis, and resistance to therapy. However, the contribution of stromal cells to non-small-cell lung cancer (NSCLC) has remained underexplored. We used an orthotopic model of Kras-driven NSCLC to systematically dissect the contribution of specific hematopoietic stromal cells in lung cancer. RNA deep-sequencing analysis of individually sorted myeloid lineage and tumor epithelial cell ...[more]