Sort   by:  
 Page size 
UnknownDesign, microwave-assisted synthesis, bioactivity and SAR of novel substituted 2-phenyl-2-cyclohexanedione enol ester derivatives.
Not available
S-EPMC9080744 | biostudies-literature
TranscriptomicsInduced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects.
Multiple FTD patient-specific iPSC lines were generated for the first time, Human neurons of progranulin haploinsufficiency have been established. PGRN S116X neurons are more sensitive to kinase inhibitors-induced cell stress, which can be rescued by ectopic progranulin expression, revealing progran...
ORGANISM(S): Homo sapiens 
2012-10-25 | E-GEOD-40378 | biostudies-arrayexpress
UnknownDesign, Synthesis and Evaluation of Novel Trichloromethyl Dichlorophenyl Triazole Derivatives as Potential Safener.
Not available
S-EPMC6770657 | biostudies-literature
TranscriptomicsMutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2 [04_Cerebellun_and_brain]
Senataxin, encoded by the SETX gene, contributes to multiple aspects of gene expression, including transcription and RNA processing. Mutations in SETX cause the recessive disorder ataxia with oculomotor apraxia type 2 (AOA2) and a dominant juvenile form of amyotrophic lateral sclerosis (ALS4). To as...
ORGANISM(S): Mus musculus 
2014-09-15 | E-GEOD-61324 | biostudies-arrayexpress
TranscriptomicsMutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2 [01_fibroblasts_patientAndcarrier]
Senataxin, encoded by the SETX gene, contributes to multiple aspects of gene expression, including transcription and RNA processing. Mutations in SETX cause the recessive disorder ataxia with oculomotor apraxia type 2 (AOA2) and a dominant juvenile form of amyotrophic lateral sclerosis (ALS4). To as...
ORGANISM(S): Homo sapiens 
2014-09-15 | E-GEOD-61320 | biostudies-arrayexpress
TranscriptomicsMutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2 [03_AOA2_patient_blood_2011]
Senataxin, encoded by the SETX gene, contributes to multiple aspects of gene expression, including transcription and RNA processing. Mutations in SETX cause the recessive disorder ataxia with oculomotor apraxia type 2 (AOA2) and a dominant juvenile form of amyotrophic lateral sclerosis (ALS4). To as...
ORGANISM(S): Homo sapiens 
2014-09-15 | E-GEOD-61322 | biostudies-arrayexpress
TranscriptomicsMutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2 [02_fibroblasts_transfected]
Senataxin, encoded by the SETX gene, contributes to multiple aspects of gene expression, including transcription and RNA processing. Mutations in SETX cause the recessive disorder ataxia with oculomotor apraxia type 2 (AOA2) and a dominant juvenile form of amyotrophic lateral sclerosis (ALS4). To as...
ORGANISM(S): Homo sapiens 
2014-09-15 | E-GEOD-61321 | biostudies-arrayexpress
UnknownInflammation of central nervous system fiber tracts is active in patients over six months post-intracerebral hemorrhage.
Not available
S-EPMC12542097 | biostudies-literature
TranscriptomicsMicroarray and Pathway Analysis Reveal Distinct Mechanisms Underlying Cannabinoid-Mediated Modulation of LPS-Induced Activation of BV-2 Microglial Cells
Cannabinoids are known to exert immunosuppressive activities. However, the mechanisms which contribute to these effects are unknown. Using lipopolysaccharide (LPS) to activate BV-2 microglial cells, we examined how Δ9-tetrahydrocannabinol (THC), the major psychoactive component of marijuana, and can...
ORGANISM(S): Mus musculus 
2015-07-09 | E-GEOD-70689 | biostudies-arrayexpress
UnknownSolvent-Free Synthesis and Safener Activity of Sulfonylurea Benzothiazolines.
Not available
S-EPMC6151413 | biostudies-literature
Sort   by:  
 Page size