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This experiment was conducted to identify target genes of the microRNA-499 in skeletal muscle of transgenic mice that overexpressed miR-499. The following abstract from the submitted manuscript describes the major findings of this work. Coupling of mitochondrial function and skeletal muscle f...
ORGANISM(S): Mus musculus 
We performed a label-free quantitative proteomic profiling to determine the effect of Polygonum perfoliatum L. treated the proteomics profile of liver tissue and identified activated PPARs/CPT1A/CPT2-mediated hepatic fatty acid β oxidation process was significantly altered
ORGANISM(S): Mus Musculus 
2024-02-05 | PXD033219 |

Application of mass spectrometry enables the detection of metabolic differences between organisms with different nutritional settings. Divergence in the metabolic fingerprints of rat pancreatic INS-1 β-cells were systematically captured with regard to 10 individual essential amino acid (EAA) avai...

2022-05-24 | MTBLS3963 | MetaboLights
The JAK/STAT pathway is an essential signalling cascade required for multiple processes during both development and for adult homeostasis. A key question in understanding this pathway is how it is regulated in different cell contexts. Here we have examined how endocytic processing contributes to sig...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2020-09-29 | PXD020719 | Pride
Background Hypothyroidism is a common disease, and its molecular mechanism still needs further investigation. Succinylation, as a newly identified protein posttranslational modification, is found to be involved in various metabolisms and cellular processes. In the present study, we performed quantit...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-08 | PXD012814 | Pride
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