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TranscriptomicsProgramming and inheritance of parental DNA methylomes in mammals
The reprogramming of parental methylomes is essential for embryonic development. In mammals, paternal 5-methylcytosines (5mCs) have been proposed to be actively converted to oxidized bases. These paternal oxidized bases and maternal 5mCs are believed to be passively diluted by cell divisions. By gen...
ORGANISM(S): Mus musculus 
2014-05-12 | E-GEOD-56697 | biostudies-arrayexpress
UnknownContrasting Health Outcomes following a Severe Smoke Episode and Ambient Air Pollution in Early Life: Findings from an Australian Data Linkage Cohort Study of Hospital Utilization.
Not available
S-EPMC10644899 | biostudies-literature
TranscriptomicsPreprocessed reduced representation bisulfite sequencing (RRBS) data from 173 human umbilical cord blood samples, collected for a study on associations between perinatal DNA methylation marks and progression to type 1 diabetes by age 15
The samples were collected from the participants of the Finnish Diabetes Prediction and Prevention (DIPP) Study, born between 1995 and 2006. DIPP is a prospective follow-up cohort of children with a moderate or high risk of type 1 diabetes, based on the HLA-DR-DQ genotype. Islet cell autoantibodies ...
ORGANISM(S): Homo sapiens 
2022-06-06 | E-MTAB-10530 | biostudies-arrayexpress
UnknownRandomised controlled trial to investigate the effectiveness of thoracic epidural and paravertebral blockade in reducing chronic post-thoracotomy pain (TOPIC): a pilot study to assess feasibility of a large multicentre trial.
Not available
S-EPMC6624049 | biostudies-literature
TranscriptomicsPhenotypic and transcriptional analysis of the osmotic regulator OmpR in Yersinia pestis
Background The osmotic regulator OmpR in Escherichia coli regulates differentially the expression of major porin proteins OmpF and OmpC. In Yersinia enterocolitica and Y. pseudotuberculosis, OmpR is required for both virulence and survival within macrophages. However, the phenotypic and regulatory r...
ORGANISM(S): Yersinia pestis 
2011-10-23 | E-GEOD-26601 | biostudies-arrayexpress
TranscriptomicsPF4-Cre mediated deletion of SRF in murine megakaryocytes.
Srf is a MADS-box transcription factor that is critical for muscle differentiation. Its function in hematopoiesis has not yet been revealed. Mkl1, a cofactor of Srf, is part of the t(1;22) translocation in acute megakaryoblastic leukemia, and plays a critical role in megakaryopoiesis. In order to te...
ORGANISM(S): Mus musculus 
2010-07-13 | E-GEOD-21859 | biostudies-arrayexpress
UnknownThe RESPITE trial: remifentanil intravenously administered patient-controlled analgesia (PCA) versus pethidine intramuscular injection for pain relief in labour: study protocol for a randomised controlled trial.
Not available
S-EPMC5153689 | biostudies-literature
UnknownPatient experience and reflective learning (PEARL): a mixed methods protocol for staff insight development in acute and intensive care medicine in the UK.
Not available
S-EPMC6661565 | biostudies-literature
UnknownAcute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial.
Not available
S-EPMC6201750 | biostudies-literature
UnknownMortality after surgery in Europe: a 7 day cohort study.
Not available
S-EPMC3493988 | biostudies-literature
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