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Affinity-capture proteomics studies using endogenously tagged G3BP1 with APEX2 to capture the stress granule proteome at steady state and upon stress induction. This was done in 293T cells as well as induced pluripotent stem cells differentiated into neuronal progenitor cells.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
The project investigated the role of CHTOP in the regulation of neuronal cell death after brain injury. To investigate the mechanism of CHTOP in the regulation of neuronal death, we performed immunoprecipitation to pulldown CHTOP interacting proteins in both neurons and other brain resident cells. T...
ORGANISM(S): Mus Musculus 
2023-02-23 | PXD040340 |
The diffuse-type gastric cancer (DGC) constitutes a subgroup of gastric cancer with poor prognosis and no effective molecular therapies. Here, we report a phosphoproteomic landscape of DGC derived from 83 tumors together with their nearby tissues. Based on phosphorylation, DGC could be classified in...
ORGANISM(S): Homo Sapiens 
2020-03-31 | PXD018293 |
We established deep-coverage thyroid-specific spectral libraries encompassing over 12,000 proteins, including samples from nine types of thyroid primary and lymph node metastases tissues and fifty thyroid cancer cell lines.
ORGANISM(S): Homo Sapiens 
2024-09-27 | PXD051051 |
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