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TranscriptomicsMethylated DNA immunoprecipitation coupled with NimbleGen's array to identify methylated genes in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is a highly invasive cancer with a poor prognosis. Using methylated DNA immunoprecipitation (MeDIP)-chip analysis, we found that 161 genes that were specifically hypermethylated in PANC-1 cells. Among them, miR-615-5p was hypermethylated in its putative promot...
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-44738 | biostudies-arrayexpress
MetabolomicsSpermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
In castration-resistant prostate cancer (CRPC), clinical response to androgen receptor (AR) antagonists is limited mainly due to AR-variants expression and restored AR signaling. The metabolite spermine is most abundant in prostate and it decreases as prostate cancer progresses, but its functions re...
2023-10-11 | MTBLS8034 | MetaboLights
TranscriptomicsIdentifying microRNA-mRNA regulatory networks in colorectal cancer by a combination of expression profile and bioinformatics analysis
A multi-step approach combining microarray profile and bioinformatics analysis was adopted to identify the CRC specific miRNA-mRNA regulatory network. First, differentially expressed miRNAs and mRNAs were found out in CRC samples compared with normal epithelial tissues by miRNA and mRNA microarray r...
ORGANISM(S): Homo sapiens 
2013-01-03 | E-GEOD-35982 | biostudies-arrayexpress
ProteomicsProteomic analysis of carbapenem-resistant Klebsiella pneumoniae exposure to tigecycline and aminoglycosides
Proteomic analysis of carbapenem-resistant Klebsiella pneumoniae exposure to tigecycline and aminoglycosides
ORGANISM(S): Klebsiella Pneumoniae Subsp. Pneumoniae Hs11286 
2022-01-17 | PXD031030 |
ProteomicsNeuroprotective Effects of Desert Organic Milk Exosomes Against LPS-Induced Cognitive Impairment: Involvement of Microglial M2 Polarization and AMPK Signaling
Hippocampal neuroinflammation (HNF) is a key pathological feature in neurodegenerative disorders. Milk-derived exosomes are bioactive extracellular vesicles, yet their potential to regulate neuroinflammatory responses in the brain remains underexplored. This study aimed to characterize the superior ...
ORGANISM(S): Bos Taurus 
2025-12-11 | PXD071863 |
UnknownAdvances in the Application of Perovskite Materials.
Not available
S-EPMC10333173 | biostudies-literature
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