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TranscriptomicsTranscription profiling of human oocytes
The identification of genes and deduced pathways from the mature human oocyte can help us better understand oogenesis, folliculogenesis, fertilization, and embryonic development. Human metaphase II oocytes were used within minutes after removal from the ovary, and its transcriptome was compared with...
ORGANISM(S): Homo sapiens 
2008-10-21 | E-GEOD-12034 | biostudies-arrayexpress
UnknownEarly goal-directed therapy using a physiological holistic view: the ANDROMEDA-SHOCK-a randomized controlled trial.
BACKGROUND:Septic shock is a highly lethal condition. Early recognition of tissue hypoperfusion and its reversion are key factors for limiting progression to multiple organ dysfunction and death. Lactate-targeted resuscitation is the gold-standard under current guidelines, although it has several pi...
S-EPMC5913056 | biostudies-literature
UnknownDistance sampling surveys reveal 17 million vertebrates directly killed by the 2020's wildfires in the Pantanal, Brazil.
Anthropogenic factors have significantly influenced the frequency, duration, and intensity of meteorological drought in many regions of the globe, and the increased frequency of wildfires is among the most visible consequences of human-induced climate change. Despite the fire role in determining bio...
S-EPMC8677733 | biostudies-literature
UnknownA trial of intracranial-pressure monitoring in traumatic brain injury.

Background

Intracranial-pressure monitoring is considered the standard of care for severe traumatic brain injury and is used frequently, but the efficacy of treatment based on monitoring in improving the outcome has not been rigorously assessed.

Methods

We conducted a multicenter, con...
S-EPMC3565432 | biostudies-literature
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