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ProteomicsProteomic analysis of human sepsis monocytes
In this project we performed a comprehensive exploration of monocyte molecular responses in a cohort of patients with septic shock via label-free shotgun proteomics. We enrolled adult (≥18 years old) patients with sepsis from community-acquired infections, diagnosed according to the Third Internatio...
ORGANISM(S): Homo sapiens (Human) 
2021-09-07 | PXD023938 | Pride
Human Blood Sepsis Monocyte Infection Septic shock 
ProteomicsProteome of extracellular vesicles from plasma of COVID-19 patients
Background: Extracellular vesicles are a valuable source of biomarkers and display the pathophysiological status of various diseases. In COVID-19, EVs are explored in several studies for their ability to reflect molecular changes caused by SARS-CoV-2 infection and impacts on disease progression. Met...
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD032808 | Pride
Covid-19 Extracellular vesicles Proteome 
ProteomicsPLATELET PROTEOME REVEALS FEATURES OF CELL DEATH, ANTIVIRAL RESPONSE AND VIRAL REPLICATION IN COVID-19.
This article provides the first proteomic analysis of platelets from COVID-19 patients. Our dataset shows that platelets are reprogrammed during severe COVID-19 and respond with the activation of type I interferon and cell death pathways, indicating platelet participation in the antiviral response. ...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD031251 | Pride
Proteome Platelet Covid-19 
TranscriptomicsBAC CGH array profiling using Phi29-amplified colon mucosa of microdissected samples from APC and MYH mutation carriers.
Details of the series are available in the publication Cardoso J. et al., “Chromosomal instability in MYH- and APC-mutant adenomatous polyps”, Cancer Research, accepted for publication. Abstract of the publication: “The vast majority of colorectal cancers display genetic instability, either in...
ORGANISM(S): Homo sapiens 
2010-06-30 | E-GEOD-3898 | biostudies-arrayexpress
UnknownA fatal mitochondrial disease is associated with defective NFU1 function in the maturation of a subset of mitochondrial Fe-S proteins.
Not available
S-EPMC3213398 | biostudies-literature
UnknownMild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses.
Not available
S-EPMC9662821 | biostudies-literature
GenomicsAlzheimer's Disease Sequencing Project (ADSP)

The overarching goals of the ADSP are to: (1) identify new genomic variants contributing to increased risk of developing AD, (2) identify new genomic variants contributing to protection against developing AD, and (3) provide insight as to why individuals with known risk factor variants escape fro...

phs000572.v1.p1 | EGA
UnknownContributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants.
Not available
S-EPMC6005056 | biostudies-literature
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