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TranscriptomicsCGH profiles of primary breast carcinomas from HBOC (Hereditary Breast and Ovarian Cancer) families
89 tumors from women that were eligible for, and subjected to, routine diagnostic testing according to the HBOC criteria but were negative for pathogenic BRCA1/2-mutations or carried an UV in either BRCA1/2 A BRCA2-classifier was built using array-CGH profiles of 28 BRCA2-mutated and 28 sporadic bre...
ORGANISM(S): Homo sapiens 
2010-07-05 | E-GEOD-22481 | biostudies-arrayexpress
TranscriptomicsAutomated array-CGH optimized for archival formalin-fixed, paraffin-embedded tumor material
BACKGROUND: Array Comparative Genomic Hybridization (aCGH) is a rapidly evolving technology that still lacks complete standardization. Yet, it is of great importance to obtain robust and reproducible data to enable meaningful multiple hybridization comparisons. Special difficulties arise when aCGH i...
ORGANISM(S): Homo sapiens 
2010-06-12 | E-GEOD-7122 | biostudies-arrayexpress
ProteomicsA proteome-integrated, carbon source dependent genetic regulatory network in Saccharomyces cerevisiae
We propose a carbon source dependent genetic regulatory network for the budding yeast Saccharomyces cerevisiae, derived from quantitative proteomic analyses integrated with bioinformatics knowledge of regulatory pathways and protein interactions. The proposed network, comprising 1247 transcription f...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-03-22 | PXD009420 | Pride
Proteomics Shotgun proteomics Regulatory network Yeast S. cerevisiae 
UnknownHepatic levels of S-adenosylmethionine regulate the adaptive response to fasting.
Not available
S-EPMC10432853 | biostudies-literature
ProteomicsWhole-cell modeling in yeast predicts compartment-specific proteome constraints that drive metabolic strategies
Our comprehensive model identifies condition-dependent and compartment-specific constraints that can explain metabolic strategies and protein expression profiles from growth rate optimization, providin a framework to understand metabolic adaptation in eukaryal cells.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-01-24 | PXD030003 | Pride
Genetic regulation Ms/ms Metabolic networks 
TranscriptomicsGene expression profiling of lung adenocarcinomas and normal lung tissue
Lung cancer is still the leading cause of cancer-related deaths in the US and worldwide. Understanding the global molecular profiles or transcriptome of lung cancers would strengthen our understanding of the biology of this malignancy. We performed gene expression profiling using the Human Gene 1.0 ...
ORGANISM(S): Homo sapiens 
2013-08-06 | E-GEOD-43458 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization by array of Ectocarpus siliculosus control reference reference hybridization
Reference reference hybridization with Ectocarpus siliculosus (strain Es 32) genomic DNA; Quality control for submission E-TABM-766
ORGANISM(S): Ectocarpus siliculosus 
2010-04-27 | E-TABM-967 | biostudies-arrayexpress
UnknownA new acquisition protocol for conducting studies with children: The science camp research experience.
Not available
S-EPMC10411783 | biostudies-literature
UnknownSymmetry breaking of fluorophore binding to a G-quadruplex generates an RNA aptamer with picomolar KD.
Not available
S-EPMC11317130 | biostudies-literature
UnknownIbrutinib Displays Atrial-Specific Toxicity in Human Stem Cell-Derived Cardiomyocytes.
Not available
S-EPMC6524928 | biostudies-literature
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