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MetabolomicsN-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression
Various cancers such as colorectal cancer (CRC) are associated with alterations in protein glycosylation. CRC cell lines are frequently used to study these (glyco)biological changes and their mechanisms. However, differences between CRC cell lines with regard to their glycosylation have hitherto bee...
2017-02-03 | MTBLS227 | MetaboLights
UnknownAURORA A interacts with DICER and SETD2 to promote S-phase progression
Not available
S-SCDT-10_1038-S44319-026-00850-0 | biostudies-other
TranscriptomicsComparison of granulosa cells from WT and Inha KO mice following gonadotropin stimulation
Inhibin α knockout (Inha-/-) female mice develop sex cord-stromal ovarian cancer with complete penetrance and previous studies demonstrate that the pituitary gonadotropins [follicle stimulating hormone (FSH) and luteinizing hormone (LH)] are influential modifiers of granulosa cell tumor development ...
ORGANISM(S): Mus musculus 
2011-02-01 | E-GEOD-20466 | biostudies-arrayexpress
TranscriptomicsAgilent 244A aCGH array for comparison of lung tumor CNA to high-throughput sequencing data
1 lung tumor was profiled for copy-number alterations with the high-resolution Agilent 244A aCGH Array. One lung tumor sample were assayed on the Agilent Human Genome CGH 244A Microarrays with the intent of comparing the genomic alterations reported by the array platform with those reported by high-...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-20574 | biostudies-arrayexpress
TranscriptomicsArrayCGH of human hepatocellular carcinoma (HCC)
We used array-based comparative genomic hybridization (arrayCGH) of 76 hepatocellular carcinomas (HCCs) to search for genetically disrupted genes. Seventy-six HCC clinical specimens were analyzed. Genomic DNA of the tumor sample was labeled with Cy5 and reference normal DNA (Promega) was labeled wit...
ORGANISM(S): Homo sapiens 
2012-01-20 | E-GEOD-14322 | biostudies-arrayexpress
Transcriptomics5q21 tiling array on prostate tumors
CGH profiles of prostate tumors on custom designed high resolution arrays tiling chromosome 5q21 A custom high-density Agilent 15k CGH array tiling 5q21 was designed to narrow down the region of deletion at 5q21 to a few genes that could be followed up with functional studies. 8 critical prostate t...
ORGANISM(S): Homo sapiens 
2011-12-19 | E-GEOD-29228 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung samples from mouse and rat treated with mechanical ventilation
This series contain mouse and rat lung samples treated with mechanical ventilation and corresponded controls.
ORGANISM(S): Mus musculus 
2007-07-20 | E-GEOD-2368 | biostudies-arrayexpress
TranscriptomicsaCGH profiling of prostate tumors
This experiment was an aCGH study on 86 prostate tumors samples. The samples were profiled on Agilent Human Genome 44karrays to identify recurrent regions of deletion and amplification, thus revealing potential new tumor suppressor genes and/or oncogenes involved in prostate cancer. The CGH profile ...
ORGANISM(S): Homo sapiens 
2011-12-19 | E-GEOD-29227 | biostudies-arrayexpress
TranscriptomicsExpression profiling of Ewing sarcoma samples
Expression profiling of Ewing sarcoma samples in the frame of the CIT program from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). Ewing sarcoma a rare pediatric tumor characterized by EWSR1-ETS fusions, is predominantly observed in populations of European ancestry. A geno...
ORGANISM(S): Homo sapiens 
2012-02-11 | E-GEOD-34620 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat mechanically ventilated lungs from strains resistant or susceptible to ventilation-associated lung injury (VALI)
We sought to confirm the genetic influence in the development of Ventilation-Associated Lung Injury (VALI) and, in the process, identify potential candidate genes involved in the disease by integrating differential gene expression profiling on rat lungs to a traditional strain survey analysis of the...
ORGANISM(S): Rattus norvegicus 
2007-10-31 | E-GEOD-7041 | biostudies-arrayexpress
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