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TranscriptomicsTranscript analyses of cisplatin and Sky1 effects in Saccharomyces cerevisiae
Sky1 is a Saccharomyces cerevisiae rich serine-arginine (SR) protein-specific kinase and its enzymatic activity is essential in the cytotoxicity caused by cisplatin, although the molecular mechanisms supporting this function are not understood. We present a transcriptome analysis discriminating betw...
ORGANISM(S): Saccharomyces cerevisiae 
2014-08-01 | E-GEOD-41094 | biostudies-arrayexpress
TranscriptomicsFunctional analysis of Arabidopsis ARGONAUTE1 using a slicer-defective mutant: Small RNA immunoprecipitation
The Arabidopsis ARGONAUTE (AGO) protein AGO1 associates with microRNA (miRNA) and specific classes of short-interfering RNA (siRNA). AGO1-small RNA complexes recognize target RNA transcripts through base-pairing interactions and inhibit translation of target RNAs through endonucleolytic cleavage (sl...
ORGANISM(S): Arabidopsis thaliana 
2012-09-28 | E-GEOD-40258 | biostudies-arrayexpress
TranscriptomicsFunctional analysis of Arabidopsis ARGONAUTE1 using a slicer-defective mutant: Transcript immunoprecipitation
The Arabidopsis ARGONAUTE (AGO) protein AGO1 associates with microRNA (miRNA) and specific classes of short-interfering RNA (siRNA). AGO1-small RNA complexes recognize target RNA transcripts through base-pairing interactions and inhibit translation of target RNAs through endonucleolytic cleavage (sl...
ORGANISM(S): Arabidopsis thaliana 
2012-09-28 | E-GEOD-40256 | biostudies-arrayexpress
TranscriptomicsGlobal identification of Arabidopsis thaliana ARGONAUTE1-associated small RNA.
Small RNA from total RNA (input fraction) and immunoprecipitated HA-AGO1-complexes (IP fraction) were identified using high-throughput sequencing-by-synthesis. Two replicate input fraction samples were used as controls for two replicate IP fraction samples. Total RNA from input fractions and small R...
ORGANISM(S): Arabidopsis thaliana 
2010-06-21 | E-GEOD-22252 | biostudies-arrayexpress
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