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TranscriptomicsTranscription profiling by array of human MCF-7 breast cancer cells
Estrogen-responsive genes were identified by transcript profiling of estrogen-treated MCF-7 breast cancer cells. The gene expression profile generated after estrogen treatment was compared with that following inducible expression of c-Myc or c-Zip (a deletion mutant of c-Myc that lacks the N-termina...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-11791 | biostudies-arrayexpress
TranscriptomicsDeep-transcriptome and ribonome sequencing redefines the molecular networks of pluripotency and the extracellular space in human Embryonic Stem cells
Cytoplasmic polyadenylated RNA from human embryonic stem cells (HES2) was separated on a 1.2% agarose and gel slices were excised corresponding to the following sizes: 0 to 0.5 kb; 0.5-2 kb; 2-3.5 kb; 3.5-6.5 kb and 6.5-20+ kb. Slices were dissolved and extracted RNA (1% of each fraction) was run on...
ORGANISM(S): Homo sapiens 
2010-10-20 | E-GEOD-24355 | biostudies-arrayexpress
TranscriptomicsLrig2 is required for maturation of peripheral nerves in the urinary bladder
Leucine-rich-repeats and immunoglobulin-like-domains (LRIG2) variants can occur in urofacial syndrome (UFS), an inherited disease characterised by functional bladder outlet obstruction. We aimed to define the pathobiology underlying UFS which we hypothesised would illuminate how the bladder becomes ...
ORGANISM(S): Mus musculus 
2020-04-27 | E-MTAB-6089 | biostudies-arrayexpress
UnknownSerum cholesterol and the progression of Parkinson's disease: results from DATATOP.
Not available
S-EPMC3154909 | biostudies-literature
no omics definedTranscription profiling of fresh and frozen rat liver RNA samples to explore how RNA quality affects microarray results
To systemically explore how RNA quality affects microarray assay results, a set of rat liver RNA samples with a progressive change in RNA quality was generated either by thawing frozen tissue or by ex vivo incubation of fresh tissue.
ORGANISM(S): Rattus norvegicus 
2007-09-01 | E-MEXP-1069 | biostudies-arrayexpress
TranscriptomicsPlatform comparison and transcription profiling of mixed tissue RNA samples formulated to contain different ratios of RNA for each of four rat tissues (brain, liver, kidney, and testes) on Affymetrix RAE230A, CodeLink UniSet Rat I, and Agilent G4130A rat oligonucleotide arrays
This experiment is a test of a reagent that can provide a basis for performance assessments on Affymetrix RAE230A, CodeLink UniSet Rat I, and Agilent G4130A rat oligonucleotide arrays. The reagent is a set of two mixed tissue RNA samples formulated to contain different ratios of RNA for each of f...
ORGANISM(S): Rattus norvegicus 
2010-03-30 | E-TABM-16 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat mixed-tissue RNA samples over 8.5 months to monitor processing drift
Process drift at one site was monitored by assaying the rat Mixed Tissue RNA Reference Material (see E-TABM-16) multiple times a week for 8.5 months.
ORGANISM(S): Rattus norvegicus 
2008-04-16 | E-MEXP-1565 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat mixed-tissue RNA samples using different labeling protocols
At one site (#10), three different batches of MTRRM (see E-TABM-16), were labeled with two different kits (Enzo and Affymetrix) and hybridized to two different Affymetrix Arrays (RAE230A and RAE230_2).
ORGANISM(S): Rattus norvegicus 
2008-04-16 | E-MEXP-1563 | biostudies-arrayexpress
UnknownA resource of targeted mutant mouse lines for 5,061 genes.
Not available
S-EPMC8397259 | biostudies-literature
UnknownThe Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update.
Not available
S-EPMC6415767 | biostudies-literature
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