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Example dataset for Methods in Enzymology Chapter - Molecular Networking-based Strategies in Mass Spectrometry Coupled with Gene Cluster Analysis and In silico Dereplication of Peptidic Natural Products. This dataset includes the LC-MS/MS raw data (centroided, lock-mass calibrated mzXML file format)...
ORGANISM(S): Burkholderia Sp. (ncbitaxon:36773) 
2021-08-17 | MSV000087997 | GNPS
Infections by Burkholderia cenocepacia lead to life-threatening disease in immunocompromised individuals, including those living with cystic fibrosis (CF). While genetic variation in various B. cenocepacia strains has been reported, it remains unclear how environmental conditions found in the CF lun...
ORGANISM(S): Burkholderia Cenocepacia (ncbitaxon:95486) 
2021-07-11 | MSV000087793 | GNPS
Metabolomic study of B. cenocepacia J2315 (produces pyomelanin) and K56-2 (lacks pyomelanin) WT strains and mutant strains in which the pyomelanin production phenotype are reversed were cultured in synthetic CF sputum media (SCFM2). Metabolites were extracted from cultures via ethyl acetate and C18 ...
ORGANISM(S): Burkholderia Cenocepacia K56-2valvano (ncbitaxon:985076) Burkholderia Cenocepacia J2315 (ncbitaxon:216591) 
2022-04-13 | MSV000089255 | GNPS
Extraction samples of murine airways epithelial LA-4 cells and murine macrophage RAW264.7 cells cultures exposed to different amounts of B. thailandensis for varying periods of time. Extracts of the adherent cells and their respective conditioned media were analyzed with LC-MS/MS to identify compoun...
ORGANISM(S): Burkholderia Thailandensis E264 (ncbitaxon:271848) Murine Airway Epithelial La-4 Murine Macrophage Raw264.7 
2022-01-17 | MSV000088693 | GNPS
Extraction samples of Bacillus spp. and B. thailandensis in mono and co-culture. Extracts were analyzed with LC-MS/MS to identify compounds detected within the aforementioned samples. Included are extracts of B. thailandensis monocultures, several Bacillus spp. monocultures, and co-cultures of B. t...
ORGANISM(S): Bacillus Subtilis (ncbitaxon:1423) Paenibacillus Lactis (ncbitaxon:228574) Bacillus Nealsonii (ncbitaxon:115979) Virgibacillus Pantothenticus (ncbitaxon:1473) Burkholderia Thailandensis E264 (ncbitaxon:271848) Bacillus Clausii (ncbitaxon:79880) Bacillus Velezensis (ncbitaxon:492670) Bacillus Licheniformis (ncbitaxon:1402) Bacillus Simplex (ncbitaxon:1478) Bacillus Megaterium (ncbitaxon:1404) Brevibacillus Borstelensis (ncbitaxon:45462) 
2022-12-27 | MSV000090970 | GNPS
The Burkholderia cepacia complex is a group of closely related species with large genomes that infect immunocompromised individuals or those living with cystic fibrosis. Some of these species are found more frequently and cause more severe disease than others, yet metabolomic differences between the...
ORGANISM(S): Burkholderia Sp. (ncbitaxon:36773) 
2020-02-11 | MSV000084945 | GNPS
The mechanisms whereby the crucial pluripotency transcription factor Oct4 regulates target gene expression are incompletely understood. Using an assay system based on partially differentiated embryonic stem cells, we show that Oct4 opposes accumulation of local H3K9me2, and subsequent Dnmt3a-mediate...
ORGANISM(S): Mus musculus 
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