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GenomicsTDP-1, the C. elegans ortholog of TDP-43, limits the accumulation of double stranded RNA
C. elegans mutants deleted for TDP-1, an ortholog of the neurodegeneration-associated RNA binding protein TDP-43, display only mild phenotypes. Nevertheless, transcriptome sequencing revealed that many RNAs were altered in accumulation and/or processing in the mutant. Analysis of these transcription...
ORGANISM(S): Caenorhabditis elegans 
2014-11-19 | E-GEOD-61581 | biostudies-arrayexpress
GenomicsLocalization of RNAPII and 3’ end formation factor CstF subunits on C. elegans genes and operons [ChIP-seq]
Transcription termination is mechanistically coupled to pre-mRNA 3’ end formation to prevent transcription much beyond the gene 3’ end. C. elegans, however, engages in polycistronic transcription of operons in which 3’ end formation between genes is not accompanied by termination. We have perf...
ORGANISM(S): Caenorhabditis elegans 
2016-04-02 | E-GEOD-79821 | biostudies-arrayexpress
TranscriptomicsLocalization of RNAPII and 3’ end formation factor CstF subunits on C. elegans genes and operons [RNA-seq]
Transcription termination is mechanistically coupled to pre-mRNA 3’ end formation to prevent transcription much beyond the gene 3’ end. C. elegans, however, engages in polycistronic transcription of operons in which 3’ end formation between genes is not accompanied by termination. We have perf...
ORGANISM(S): Caenorhabditis elegans 
2016-04-02 | E-GEOD-79822 | biostudies-arrayexpress
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