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We investigated which signaling pathways downstream of Gas6/Axl promote the invasive phenotype of liver cancer cells. Thus, we performed phospho-proteomic analysis of MR hepatocytes and those expressing Axl (MR-Axl) in the presence and absence of Gas6. Protein-clustering based on the pattern of phos...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-23 | PXD047577 | Pride
Gas6 promotes Cardiomyocyte Proliferation and Heart Regeneration
Potential role of gas6 in zebrafish hindbrain development
Differential Gene Expression between YTN16 Gas6 Cells and YTN16 Cells
GAS6 drives chemoresistance and immune escape in ovarian cancer
Overexpression and amplification of AXL receptor tyrosine kinase (RTK) has been found in several hematologic and solid malignancies. Activation of AXL by its ligand GAS6 can enhance tumor-promoting processes such as proliferation, migration, invasion, and survival. Despite the important role of AXL ...
ORGANISM(S): Homo sapiens (Human) 
2021-08-24 | PXD025457 | Pride
Effect of Gas6/Axl on HCC cell line gene expression
Gas6-Axl signaling drives oral regenerative wound repair
Ischemic heart disease remains a leading cause of mortality, with limited adult cardiac regeneration due to insufficient cardiomyocyte proliferation. This study investigates the role of Growth Arrest-Specific Gene 6 (Gas6) in regulating cardiomyocyte cell cycle and promoting cardiac repair. Gas6 exp...
ORGANISM(S): Mus musculus 
2026-08-21 | GSE306068 | GEO
High-grade serous ovarian cancer (HGSOC) has poor prognosis owing to widespread platinum resistance and unsatisfactory efficacy of chemo-immunotherapy, so novel mechanisms of therapeutic failure are urgently required. The GAS6/AXL axis supports tumor survival and immunosuppression, yet how chemother...
ORGANISM(S): Homo sapiens 
2026-08-03 | GSE341740 | GEO
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