Sort   by:  
 Page size 
ProteomicsPlasmodium falciparum GBP2 pulldown
This experiment was conducted to learn about the potential biological roles of P. falciparum GBP2 (PfGBP2), a protein identified as part of the telomeric proteome in the malaria parasite P. falciparum. HA-tagged GBP2 protein was immunoprecipitated from P. falciparum parasites and its interactome wa...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2022-04-04 | PXD028903 | Pride
Plasmodium Malaria Gbp2 
TranscriptomicsRNA immunoprecipitation of Plasmodium berghei coupled to RNA-sequencing of GBP2::mCherry parasites.
Identification of RNAs directly bound by malarial GBP2
ORGANISM(S): Plasmodium berghei 
2021-09-03 | E-MTAB-10775 | biostudies-arrayexpress
ProteomicsIdentification of GBP2- and NAB2-interacting proteins in malaria parasites
The quality control and export of mRNA by RNA-binding proteins are necessary for the survival of malaria parasites, which have complex life cycles. Malarial nuclear poly(A) binding protein 2 (NAB2), ALWAYS EARLY (ALY) and serine/arginine-rich (SR) proteins, such as nucleolar protein 3 (NPL3), G-stra...
ORGANISM(S): Plasmodium berghei ANKA 
2021-11-03 | PXD027302 | Pride
Lc-ms/ms 
GenomicsRNA immunoprecipitation of Plasmodium berghei coupled to RNA-sequencing of GBP2::mCherry parasites.
RNA immunoprecipitation of Plasmodium berghei coupled to RNA-sequencing of GBP2::mCherry parasites.
PRJEB46557 | ENA
GenomicsGBP2 Enhances Anti–PD-L1 Response in Colorectal Cancer by Non-Pyroptotic Inhibition of GSDMD-Mediated YAP Activation
GBP2 Enhances Anti–PD-L1 Response in Colorectal Cancer by Non-Pyroptotic Inhibition of GSDMD-Mediated YAP Activation
PRJNA1308496 | ENA
TranscriptomicsGBP2 Enhances Anti–PD-L1 Response in Colorectal Cancer by Non-Pyroptotic Inhibition of GSDMD-Mediated YAP Activation
Guanylate-binding protein 2 (GBP2), a member of the GTPase family, has emerged as a critical regulator of the tumor immune microenvironment (TIME) in colorectal cancer (CRC). In this study, we investigated the biological functions of GBP2 and its impact on immune checkpoint blockade (ICB) therapy. M...
ORGANISM(S): Homo sapiens 
2026-08-30 | GSE305943 | GEO
TranscriptomicsQuality control of spliced mRNAs requires the shuttling SR-proteins Gbp2 and Hrb1
Eukaryotic cells have to prevent the export of unspliced pre-mRNAs until intron removal is completed to avoid the expression of aberrant and potentially harmful proteins. Only mature RNAs associate with the export receptor Mex67 (mammalian TAP) and enter the cytoplasm. The underlying nuclear quality...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-04 | E-GEOD-52808 | biostudies-arrayexpress
UnknownGBP2 as a potential prognostic biomarker in pancreatic adenocarcinoma.
Not available
S-EPMC8121056 | biostudies-literature
TranscriptomicsThe shuttling SR-like proteins Gbp2 and Hrb1 mediate the nuclear export of spliced mRNAs
Three shuttling SR-like proteins exist in Saccharomyces cerevisiae, Npl3, Gbp2 and Hrb1, that are involved in the nuclear export of mRNAs. In a screen for genes that regulate the export of Gbp2, we identified novel mutants of the splicing factors PRP8 and PRP17 that lead to severe mislocalization de...
ORGANISM(S): Saccharomyces cerevisiae 
2013-08-30 | E-GEOD-20738 | biostudies-arrayexpress
UnknownCrosstalk between GBP2 and M2 macrophage promotes the ccRCC progression.
Not available
S-EPMC11531969 | biostudies-literature
Sort   by:  
 Page size