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TranscriptomicsGenome-wide enrichment of Gcn5 and H3K18/H4K16 acetylation under physiological change of stress adaptation and stress recovery
The data provide information of Gcn5 enrichment, H3K18 and H4K16 acetylation level and Histone H3 density for 5 different physioloigcal conditions during stress adpatation and stress recovery (normal growth, during stress adaptation, after stress adaptation, under stress recovery, after stress rec...
ORGANISM(S): Saccharomyces cerevisiae 
2013-07-22 | E-GEOD-36600 | biostudies-arrayexpress
TranscriptomicsDeletion of Clr3 restores expression of a subset of genes in gcn5- mutant cells
Histone acetylation and deacetylation is important for gene regulation. The histone acetyltransferase, Gcn5, is a known activator of transcriptional initiation that is recruited to gene promoters. Here we map genome-wide levels of Gcn5 occupancy and histone H3K14ac at high resolution. Gcn5 is predom...
ORGANISM(S): Schizosaccharomyces pombe 
2010-06-24 | E-GEOD-13817 | biostudies-arrayexpress
ProteomicsMudPIT analysis of the Dbf4/Chiffon and Gcn5 complex in Drosophila
During evolution, there has been an expansion in the diversity of histone acetyltransferase Gcn5-containing complexes. All Gcn5 complexes share Sgf29 and Ada3 subunits, which together with their respective Ada2 homolog, enable nucleosomal HAT activity. In metazoans, including Drosophila, there are t...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2017-12-07 | MSV000081791 | MassIVE
GenomicsMyc and SAGA Rewire an Alternative Splicing Network During Early Somatic Cell Reprogramming [mESCs_ChIPSEQ]
Embryonic stem cells are maintained in a self-renewing and pluripotent state by multiple regulatory pathways. Pluripotent-specific transcriptional networks are sequentially reactivated as somatic cells reprogram to achieve pluripotency. How epigenetic regulators modulate this process and contribute ...
ORGANISM(S): Mus musculus 
2015-04-15 | E-GEOD-67710 | biostudies-arrayexpress
ProteomicsThe nuclear sulfenome of Arabidopsis: spotlight on histone acetyltransferase GCN5 regulation through functional thiols
In aerobic life forms, reactive oxygen species (ROS) are produced by the partial reduction of oxygen during energy-generating metabolic processes. In plants, ROS production increases during periods of both abiotic and biotic stress, severely overloading the antioxidant systems. Hydrogen peroxide (H2...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-02-20 | PXD057987 | Pride
Sulfenylation Arabidopsis Gcn5 Dimedone 
GenomicsMyc and SAGA Rewire an Alternative Splicing Network During Early Somatic Cell Reprogramming [Reprogramming_ChIPSEQ]
Embryonic stem cells are maintained in a self-renewing and pluripotent state by multiple regulatory pathways. Pluripotent-specific transcriptional networks are sequentially reactivated as somatic cells reprogram to achieve pluripotency. How epigenetic regulators modulate this process and contribute ...
ORGANISM(S): Mus musculus 
2015-04-15 | E-GEOD-67694 | biostudies-arrayexpress
TranscriptomicsMyc and SAGA Rewire an Alternative Splicing Network During Early Somatic Cell Reprogramming [Reprogramming_RNASEQ]
Embryonic stem cells are maintained in a self-renewing and pluripotent state by multiple regulatory pathways. Pluripotent-specific transcriptional networks are sequentially reactivated as somatic cells reprogram to achieve pluripotency. How epigenetic regulators modulate this process and contribute ...
ORGANISM(S): Mus musculus 
2015-04-15 | E-GEOD-67715 | biostudies-arrayexpress
TranscriptomicsComparison of gene regulation by Gcn5 under KCl stress in S. cerevisiae and S. pombe
This is parallel comparison of gene regulation by Gcn5 in evolutionarily divergent yeasts S. pombe and S. cerevisiae. Our study showed Gcn5 is required for a similar spectrum of stress responses in both organisms, including the response to KCl. This DNA microarray studies is to find conserved or div...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-24 | E-GEOD-5218 | biostudies-arrayexpress
TranscriptomicsToxoplasma gondii lysine acetyltransferase GCN5-A functions in the cellular response to alkaline stress and expression of cyst genes
Parasitic protozoa such as the apicomplexan Toxoplasma gondii progress through their life cycle in response to stimuli in the environment or host organism. Very little is known about how proliferating tachyzoites reprogram their expressed genome in response to stresses that prompt development into ...
ORGANISM(S): Toxoplasma gondii 
2011-05-25 | E-GEOD-22100 | biostudies-arrayexpress
TranscriptomicsComparison of simple mutants gcn5 and hd1 and double mutant gcn5 hd1.
rs05-09_histone-acetylase - gcn5 - Different genes show an opposed expression profile in gcn5 compared to hd1. For these genes, the double mutant might show an expression similar to the wild type. - gcn5, hd1 or double mutant gcn5hd1 were grown on MS during 10 days (1.03 boyes stage). Keywords: ge...
ORGANISM(S): Arabidopsis thaliana 
2009-04-10 | E-GEOD-15560 | biostudies-arrayexpress
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