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TranscriptomicsThe Arabidopsis Mediator CDK8 module genes CCT and GCT are global regulators of developmental phase transitions.
Temporal coordination of developmental programs is necessary for normal ontogeny, but the mechanism by which this is accomplished is poorly understood. We have previously shown that two components of the Mediator CDK8 module, CENTER CITY (CCT/MED12) and GRAND CENTRAL (GCT/MED13), are required for t...
ORGANISM(S): Arabidopsis thaliana 
2014-09-22 | E-GEOD-56155 | biostudies-arrayexpress
Transcriptomicsexpression data from pediatric primary intracranial germ cell tumor
Intracranial pediatric germ cell tumors (GCTs) have different histological differentiations, prognosis and clinical behaviors. Prognosis of patients with germinoma and mature teratoma is good, while patients with other types of GCTs, termed as nongerminomatous malignant germ cell tumors (NGMGCTs), r...
ORGANISM(S): Homo sapiens 
2010-03-09 | E-GEOD-19348 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression data from pediatric primary intracranial germ cell tumor
Intracranial pediatric germ cell tumors (GCTs) have different histological differentiations, prognosis and clinical behaviors. Prognosis of patients with germinoma and mature teratoma is good, while patients with other types of GCTs, termed as nongerminomatous malignant germ cell tumors (NGMGCTs), r...
ORGANISM(S): Homo sapiens 
2010-05-14 | E-GEOD-19347 | biostudies-arrayexpress
TranscriptomicsGenotyping and analysis of chromosome copy number variation (CNV) from pediatric primary intracranial germ cell tumor
Intracranial pediatric germ cell tumors (GCTs) have different histological differentiations, prognosis and clinical behaviors. Prognosis of patients with germinoma and mature teratoma is good, while patients with other types of GCTs, termed as nongerminomatous malignant germ cell tumors (NGMGCTs), r...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-19349 | biostudies-arrayexpress
TranscriptomicsFOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development
The Forkhead Box, FOXO1 and FOXO3, transcription factors regulate multiple functions in mammalian cells. Selective inactivation of the Foxo1 and Foxo3 genes in murine ovarian granulosa cells severely impairs follicular development and apoptosis causing infertility, and as shown herein, granulosa cel...
ORGANISM(S): Mus musculus 
2015-06-17 | E-GEOD-67662 | biostudies-arrayexpress
TranscriptomicsRNA sequencing data of primary cancer-associated fibroblasts (CAF) isolated from fresh ex vivo germ cell tumor (GCT) patient tissue
Single eng 3' RNA sequencing of primary CAF isolated from fresh ex vivo GCT patient tissue. Purity of CAF populations were verified by qPCR analysis of common CAF, GCT, endothelial and epithelial markers. 14 different CAF cultures from distinct GCT subtypes (seminoma(SE), non-seminoma(NS)) and 5 non...
ORGANISM(S): Homo sapiens 
2024-06-21 | GSE229047 | GEO
GenomicsRNA sequencing data of primary cancer-associated fibroblasts (CAF) isolated from fresh ex vivo germ cell tumor (GCT) patient tissue
RNA sequencing data of primary cancer-associated fibroblasts (CAF) isolated from fresh ex vivo germ cell tumor (GCT) patient tissue
PRJNA952637 | ENA
Methylation profilingIllumina Infinium MethylationEPIC BeadChip (850k) data of primary cancer-associated fibroblasts (CAF) isolated from fresh ex vivo germ cell tumor (GCT) patient tissue
Illumina Infinium MethylationEPIC BeadChip (850k) array analysis of DNA methylation of primary CAF isolated from fresh ex vivo GCT patient tissue. Purity of CAF populations were verified by qPCR analysis of common CAF, GCT, endothelial and epithelial markers. 14 different CAF cultures from distinct ...
ORGANISM(S): Homo sapiens 
2024-06-21 | GSE228405 | GEO
UnknownRNase P generated tRF<sup>Ser-GCT</sup> promotes fat storage in adipocytes via Adrb2 signaling.
Not available
S-EPMC12648613 | biostudies-literature
TranscriptomicsThe Arabidopsis Mediator CDK8 module genes CCT and GCT are global regulators of developmental phase transitions.
Temporal coordination of developmental programs is necessary for normal ontogeny, but the mechanism by which this is accomplished is poorly understood. We have previously shown that two components of the Mediator CDK8 module, CENTER CITY (CCT/MED12) and GRAND CENTRAL (GCT/MED13), are required for ti...
ORGANISM(S): Arabidopsis thaliana 
2014-09-22 | GSE56155 | GEO
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