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UnknownLinoleyl acetate and mandenol alleviate HUA-induced ED via NLRP3 inflammasome and JAK2/STAT3 signalling conduction in rats.
Not available
S-EPMC11381191 | biostudies-literature
UnknownModulation of NLRP3 Inflammasome Activation by QYHT Decoction: Implications for the Treatment of Erectile Dysfunction in Hyperuricemia.
Not available
S-EPMC11863226 | biostudies-literature
TranscriptomicsIntegrative regulatory mapping indicates that the RNA-binding protein HuR (ELAVL1) couples pre-mRNA processing and mRNA stability [sequence data]
RNA-binding proteins coordinate the fates of multiple RNAs, but the principles underlying these global interactions remain poorly understood. We elucidated regulatory mechanisms of the RNA-binding protein HuR, by integrating data from diverse high-throughput targeting technologies, specifically PAR-...
ORGANISM(S): Homo sapiens 
2011-08-19 | E-GEOD-29779 | biostudies-arrayexpress
TranscriptomicsChemokine Transcripts as Targets of the RNA-Binding Protein HuR in Human Airway Epithelium
HuR is a regulator of mRNA turnover or translation of inflammatory genes through binding to adenylate-uridylate-rich elements (ARE) and related motifs present in the 3’untranslated region (UTR) of mRNAs. We aimed to identify HuR targets in the human airway epithelial cell line BEAS-2B challenged wit...
ORGANISM(S): Homo sapiens 
2010-11-10 | E-GEOD-25264 | biostudies-arrayexpress
ProteomicsCrizotinib, Tyrosine Kinase Inhibitors, Create an Antibacterial Active against Gram-positive Bacteria by Targeting the CTP Synthetase PyrG
Abstract The infection of drug resistant bacteria seriously threats to public health, which makes it more urgent to find novel antibacterial compounds. Compared with traditional development approaches, drug repurposing provides a faster and more effective strategy to find new antimicrobial agents....
ORGANISM(S): Staphylococcus aureus 
2022-03-10 | PXD029546 | Pride
Infection Pyrg Keywords: crizotinib Gram-positive 
ProteomicsDetection of betalains from the extracts of H. henanensis sp. nov.
Identification of betalains from the extracts of H. henanensis sp. nov. using untargeted metabolomics.
ORGANISM(S): Tardigrada 
2024-03-22 | PXD050882 |
UnknownEpidemiological and genetic characteristics of swine pseudorabies virus in mainland China between 2012 and 2017.
Not available
S-EPMC6202975 | biostudies-literature
TranscriptomicsRMECs: hypoxia-induced group vs. paired untreated group
Objective To explore the molecular mechanisms of retinopathy of prematurity (ROP) at whole genome scale using cultivated human fetal retinal microvascular endothelial cells (RMECs) under hypoxic condition. Study design Aborted fetuses with mean gestational age of 20-28 weeks at Guangdong Women and ...
ORGANISM(S): Homo sapiens 
2014-07-17 | E-GEOD-59462 | biostudies-arrayexpress
UnknownProtein Arginine Methyltransferase 5 Inhibition Upregulates Foxp3+ Regulatory T Cells Frequency and Function during the Ulcerative Colitis.
Not available
S-EPMC5440547 | biostudies-literature
TranscriptomicsGene expression throughout vertebrate embryogenesis
This study presents statistical analyses of gene expression during all 40 developmental stages in the teleost Fundulus heteroclitus using four biological replicates per stage. Patterns of gene expression for 7,000 genes appear to be important as they recapitulate developmental timing. Among the 45...
ORGANISM(S): Fundulus heteroclitus 
2011-04-19 | E-GEOD-21372 | biostudies-arrayexpress
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