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To understand the underlying resistance mechanisms in response to imatinib (IMA) and adriamycin (ADR), the parental K562 cells were treated with low doses of IMA or ADR for two months to generate derivative cells with mild, intermediate and severe resistance to the drugs as defined by their increasi...
ORGANISM(S): Homo Sapiens 
2021-12-21 | PXD030553 |
264 DDA files corresponding to 36 mouse organs; PulseDIA data profiling of 41 male mouse organs and nine pairs of organs
ORGANISM(S): Mus Musculus 
prostate cancer FFPE samples includes 125 injections
ORGANISM(S): Homo Sapiens 
2024-02-01 | PXD049071 |
The diagnosis of follicular-patterned thyroid tumors such as follicular adenoma (FA), follicular thyroid carcinoma (FTC), and follicular variant of papillary thyroid carcinoma (FvPTC) remains challenging. This study aimed to explore the molecular differences among these three thyroid tumors by prote...
ORGANISM(S): Homo Sapiens 
We collected 78 biopsies and analyzed the proteomic expression by pressure cycling technology and Pulsed data-independent acquisition (PCT-PulseDIA) pipeline. Next, we explore the differentially expressed proteins (DEPs) in the discovery set (n=16) which contains short (S, n=8)- and long (L, n=8)- t...
ORGANISM(S): Homo Sapiens 
2022-11-04 | PXD037951 |
Targeted mass spectrometric assays for the 22 proteins in a second test cohort containing 19 COVID-19 patients
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-30 | MSV000085515 | GNPS
Early detection and effective treatment of severe COVID-19 patients remain major challenges. Here, we performed proteomic and metabolomic profiling of sera from 46 COVID-19 and 53 control individuals. We then trained a machine learning model using proteomic and metabolomic measurements from a traini...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 (ncbitaxon:2697049) Homo Sapiens (ncbitaxon:9606) 
2020-05-29 | MSV000085507 | GNPS
we describe a protocol for pressure cycling technology (PCT) assisted tissue sample preparation for high-throughput proteomics
ORGANISM(S): Homo Sapiens Mus Musculus 
2021-12-24 | PXD030645 |
We firstly built a high-quality ovarian tissue-specific spectral library containing 130,735 peptides and 10,696 proteins on Orbitrap instruments. Compared to a published pan-human spectral library (DPHL), this spectral library provides 10% more ovary-specific and 3% more ovary-enriched proteins. Thi...
ORGANISM(S): Homo Sapiens 
2023-01-02 | PXD039160 |
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