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TranscriptomicsDMRT6 coordinates the transition between mitotic and meiotic developmental programs during mamalian spermatogenesis
In mammals, a key transition in spermatogenesis is the exit from spermatogonial differentiation and mitotic proliferation and the entry into spermatocyte differentiation and meiosis. Although several genes that regulate this transition have been identified, how it is controlled and coordinated remai...
ORGANISM(S): Mus musculus 
2014-10-31 | E-GEOD-60440 | biostudies-arrayexpress
GenomicsDUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes
Ectopic expression of the double homeodomain transcription factor DUX4 causes facioscapulohumeral muscular dystrophy (FSHD). Mechanisms of action of DUX4 are currently unknown. Using immortalized human myoblasts with a titratable DUX4 transgene, we identify by mass spectrometry an interaction betwee...
ORGANISM(S): Homo sapiens 
2016-03-10 | E-GEOD-78158 | biostudies-arrayexpress
UnknownDescriptive Analysis of Measles Transmission Among Travelers During Domestic and Inbound US International Air Travel, 2018-2019.
Not available
S-EPMC12823029 | biostudies-literature
ProteomicsOMA-1, LIN-41 IPMS - LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans
An extended meiotic prophase is a hallmark of oogenesis. Hormonal signaling activates the CDK1/cyclin B kinase to promote oocyte meiotic maturation, which involves nuclear and cytoplasmic events. Nuclear maturation encompasses nuclear envelope breakdown, meiotic spindle assembly, and chromosome segr...
ORGANISM(S): Caenorhabditis elegans 
2017-06-16 | PXD006726 | Pride
Oma-1 lin-41 ribonucleoprotein complex 
UnknownDux facilitates post-implantation development, but is not essential for zygotic genome activation†.
Not available
S-EPMC7786258 | biostudies-literature
Unknownp53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy.
Not available
S-EPMC5665455 | biostudies-literature
UnknownDux Is Dispensable for Skeletal Muscle Regeneration: A Study Inspired by a "Red Flagged" Publication and Editorial Oversight.
Not available
S-EPMC12109671 | biostudies-literature
UnknownLow level DUX4 expression disrupts myogenesis through deregulation of myogenic gene expression.
Not available
S-EPMC6240038 | biostudies-literature
UnknownDUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes.
Not available
S-EPMC4914088 | biostudies-literature
UnknownATM deficiency promotes development of murine B-cell lymphomas that resemble diffuse large B-cell lymphoma in humans.
Not available
S-EPMC4643004 | biostudies-literature
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