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Investigation of zinc hyperaccumulation in Thlaspi caerulescens using a quantitative proteomics approach
ORGANISM(S): Thlaspi caerulescens (Alpine penny-cress) (Thlaspi calaminare) 
2014-03-26 | PRD000636 | Pride
Phenotypic characterisation of our zebrafish sfpq homozygous mutants revealed a restricted set of specific defects, unexpected for a protein expressed ubiquitously and involved in such general mechanisms. The CNS was prominently affected, showing brain boundary and axonal defects associated with abs...
ORGANISM(S): Danio rerio 
Genome-wide expression profiling of the retinoschisin deficient retina in C57CL/6 mice. Experiment Overall Design: RNAs from retinae from 3 Wildtype Mice versus 3 Retinoschisin-KO mice (Rs1h-/Y) at postnatal day 7 (P7) were hybridized onto Affymetrix microarrays.
ORGANISM(S): Mus musculus 
Songbirds provide rich natural models for studying the relationships of brain anatomy, behavioral function, environmental signals and gene expression. Under the Songbird Neurogenomics Initiative, investigators from more than a dozen laboratories collected brain samples from six species of songbird ...
ORGANISM(S): Sturnus vulgaris 
GENCORD2 RNA-seq BAM files using BWA
GENCORD2 DNA methylation
204 individuals were genotyped with the Illumina 2.5M Omni chip. Filtered genotypes were imputed into the 1000 genomes project European panel SNPs. Beagle R2 is indicated in VCF files for further filtering. See Materials and Methods in publication for details.
DNA methylation is an essential1 epigenetic mark whose role in gene regulation and its dependency on genomic sequence and environment are not yet fully understood2,3. In this study we provide novel insights into the mechanistic relationships between genetic variation, DNA methylation and transcripto...
Neurodegenerative diseases of the central nervous system are characterised by pathogenetic cellular and molecular changes in specific areas of the brain that lead to the dysfunction and/or loss of explicit neuronal populations. Despite exhibiting different clinical profiles and selective neuronal lo...
ORGANISM(S): Homo sapiens 
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