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ProteomicsHuman NMDAR autoantibodies disrupt excitatory-inhibitory balance leading to hippocampal network hypersynchrony
Specific autoantibodies against the NMDA-receptor (NMDAR) GluN1 subunit cause severe and debilitating NMDAR-encephalitis. Autoantibodies induce prototypic disease symptoms resembling schizophrenia, including psychosis and cognitive dysfunction. Using a mouse passive transfer model applying human mon...
ORGANISM(S): Mus musculus (Mouse) 
2023-09-24 | PXD032055 | Pride
Network oscillation Excitatory-inhibitory imbalance Autoantibodies Nmda receptor encephalitis Nmda receptor Theta-gamma coupling Neural network modeling 
UnknownGenerate-Boost: study protocol for a prospective, multicenter, randomized controlled, double-blinded phase II trial to evaluate efficacy and safety of bortezomib in patients with severe autoimmune encephalitis.
Not available
S-EPMC7346383 | biostudies-literature
UnknownA genome-wide association study in autoimmune neurological syndromes with anti-GAD65 autoantibodies.
Not available
S-EPMC9976967 | biostudies-literature
UnknownDyadic Coping of NMOSD and MOGAD patients and their partners: a sociological and psychological examination of strategies (CoMMOnsense-Study).
Not available
S-EPMC12542533 | biostudies-literature
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