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ProteomicsAutoantibodies are abundant in all human sera: a demographic characterization via protein microarrays
Human serum samples were probed onto human protein microarrays in order to ascertain the number and diversity of naturally ocurring self-reactive IgG autoantibodies. In the study presented here, 166 human serum samples were probed onto human protein microarrays in order to identify self-reactive IgG...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-39087 | biostudies-arrayexpress
GenomicDNA methylation in SLE-related autoantibodies

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can have debilitating effects on multiple organ systems. In SLE, the pivotal immunologic disturbance is the formation of autoantibodies directed against nuclear and cellular antigens. These autoantibodies are associated with ...

phs000947 | dbGaP
ProteomicsCharacterization of A Novel Mengingoencephalomyelitis Associated with Vimentin IgG Autoantibodies
Autoantibodies are crucial for diagnosing central nervous system (CNS) autoimmune disorders. In autoimmune astrocytopathy, autoantibodies targeting astrocytes, such as those against glial fibrillary acidic protein (GFAP) or aquaporin protein 4 (AQP4), serve as indispensable diagnostic markers. Never...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-01-22 | PXD056570 | Pride
Mengingoencephalomyelitis autoantibodies 
GenomicsInterferon-λ-Neutralizing Autoantibodies and Common Autoimmune Disease Autoantibodies in Pediatric Acute-Onset Neuropsychiatric Syndrome [CTD-CC]
Interferon-λ-Neutralizing Autoantibodies and Common Autoimmune Disease Autoantibodies in Pediatric Acute-Onset Neuropsychiatric Syndrome [CTD-CC]
PRJNA1458242 | ENA
ProteomicsIgG Fc Glycosylation of Total and Disease-Specific Autoantibodies in Systemic Sclerosis
This dataset contains IgG Fc glycosylation profiles of total and antigen-specific autoantibodies from systemic sclerosis (SSc) patients and healthy controls (n = 187). Total IgG and anti-centromere protein B (ACA) and anti-topoisomerase I (ATA) IgG were affinity-purified, digested with trypsin, and ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD083619 | Pride
Human Autoantibodies Systemic sclerosis Lc-ms Plasma Igg fc glycosylation 
TranscriptomicsGenome-wide expression kinetics of children with T1D-associated autoantibodies compared to healthy matched controls I
To unravel genes and molecular pathways involved in the pathogenesis of type 1 diabetes (T1D), we performed genome-wide gene expression profiling of prospective venous blood samples from children developing T1D-associated autoantibodies or progressing towards clinical diagnosis. 63 peripheral blood ...
ORGANISM(S): Homo sapiens 
2014-02-20 | E-GEOD-30208 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression kinetics of children with T1D-associated autoantibodies compared to healthy matched controls II
To unravel genes and molecular pathways involved in the pathogenesis of type 1 diabetes (T1D), we performed genome-wide gene expression profiling of prospective venous blood samples from children developing T1D-associated autoantibodies or progressing towards clinical diagnosis. 58 peripheral blood ...
ORGANISM(S): Homo sapiens 
2014-02-20 | E-GEOD-30209 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression kinetics of children with Type 1 diabetes (T1D) -associated autoantibodies or progression towards clinical T1D, compared to healthy matched controls .
To unravel genes and molecular pathways involved in the pathogenesis of type 1 diabetes (T1D), we performed genome-wide gene expression profiling of prospective venous blood samples from children developing T1D-associated autoantibodies or progressing towards clinical diagnosis. 357 peripheral blood...
ORGANISM(S): Homo sapiens 
2014-02-20 | E-GEOD-43488 | biostudies-arrayexpress
TranscriptomicsOver expression of mRNA for multiple genes including insulin in the PLN of NOD is associated with Islet Autoimmunity
The aim of this study is to identify genes implicated in the early steps of the autoimmune process, prior to inflammation in type 1 diabetes. Early Insulin AutoAntibodies (E-IAA) have been used as subphenotypic marker to select individual animals as type 1 diabetes prone and to compare gene expressi...
ORGANISM(S): Mus musculus 
2009-10-02 | E-GEOD-15582 | biostudies-arrayexpress
GenomicsNew-Onset IgG Autoantibodies in Hospitalized Patients with COVID-19 [viral]
New-Onset IgG Autoantibodies in Hospitalized Patients with COVID-19 [viral]
PRJNA749311 | ENA
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