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TranscriptomicsTranscription profiling of C. elegans long luved daf-2 mutants for the insulin/IGF-1 receptor. daf-2(e1370) and daf-2(m577) alleles each examined as single and as double mutations with the daf-16(df50) reveals insights into longevity
Analysis of gene expression in long-lived daf-2 mutants for the insulin/IGF-1 receptor. daf-2(e1370) and daf-2(m577) alleles each examined as single and as double mutations with the daf-16(df50) allele. DAF-2 regulates DAF-16, a transcription factor. Results provide insight into longevity.
ORGANISM(S): Caenorhabditis elegans 
2007-07-05 | E-GEOD-1762 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNAseq and scTCRseq of human CD8 T cells from blood and skin compartments in Dengue patients
Using a skin-blister induction model established for dengue, we investigated the transcriptional signatures and TCR repertoire of matched CD8 T cells in skin and blood samples
ORGANISM(S): Homo sapiens 
2026-04-14 | E-MTAB-16332 | biostudies-arrayexpress
UnknownImproved resilience and proteostasis mediate longevity upon DAF-2 degradation in old age.
Not available
S-EPMC11335714 | biostudies-literature
TranscriptomicsSingle-Cell RNA-Sequencing Reveals Placental Response under Environmental Stress
This repository provides scRNA-seq data corresponding to the manuscript \\"Single-Cell RNA-Sequencing Reveals Placental Response under Environmental Stress\\" by Van Buren, Azzara, Rangel-Moreno, de la Luz Garcia-Hernandez, Murphy, Cohen, Lin, and Park. The repository includes both count by gene mat...
ORGANISM(S): Mus musculus 
2024-07-13 | E-MTAB-14214 | biostudies-arrayexpress
TranscriptomicsArray-Based Genomic Comparative Hybridization Analysis of Field Strains of Mycoplasma hyopneumoniae
Mycoplasma hyopneumoniae is the causative agent of porcine enzootic pneumonia and a major factor in the porcine respiratory disease complex. A clear understanding of the mechanisms of pathogenesis does not exist although it is clear that M. hyopneumoniae adheres to porcine ciliated epithelium by act...
ORGANISM(S): Mycoplasma hyopneumoniae 
2010-05-27 | E-GEOD-8306 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of four mouse tissues following acute caloric restriction
Multi-tissue transcriptional response following acute caloric restriction in mice.
ORGANISM(S): Mus musculus 
2007-05-17 | E-MEXP-748 | biostudies-arrayexpress
Transcriptomics10x single cell mRNA sequencing of transcervical swabs of pregnant donors at 5.2, 7.6, and 10.2 weeks of gestation
Non-invasive prenatal testing (NIPT) using cell free fetal DNA has transformed prenatal care by allowing risk assessment for a number of fetal genetic conditions without posing risk to the pregnancy. However, its limitations, including low fetal fraction and high DNA fragmentation, restrict its capa...
ORGANISM(S): Homo sapiens 
2026-05-31 | E-MTAB-15846 | biostudies-arrayexpress
TranscriptomicsDevelopment of a humanized mouse model of graft-versus-host disease to assess human regulatory T cell function
We developed a humanized mouse model of graft-versus-host disease in which Treg injected two days after PBMC persist in the blood of infused mice and can be characterized. This model provides in vivo assessment of manipulated Treg. We used that model to evaluate the impact of ex vivo priming of Treg...
ORGANISM(S): Homo sapiens 
2025-11-20 | E-MTAB-15881 | biostudies-arrayexpress
TranscriptomicsClonal hematopoiesis activates pro-calcific pathways in macrophages and promotes aortic valve stenosis
PBMCs of patients with AVS having TET2 mutations versus those with no known CHIP mutations were utilized for scRNA-seq
ORGANISM(S): Homo sapiens 
2025-10-22 | E-MTAB-15820 | biostudies-arrayexpress
TranscriptomicsTonsil Atlas FASTQ files
This repository contains all the FASTQ files for the five data modalities (scRNA-seq, scATAC-seq, Multiome, CITE-seq+scVDJ-seq, and spatial transcriptomics) used in the article \\"An Atlas of Cells in The Human Tonsil,\\" published in Immunity in 2024. Inspired by the TCGA barcodes, we have named ea...
ORGANISM(S): Homo sapiens 
2024-05-02 | E-MTAB-13687 | biostudies-arrayexpress
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