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MetabolomicsGenetic mapping and molecular mechanism behind color variation in the Asian vine snake

BACKGROUND: Reptiles exhibit a wide variety of skin colors, which serve essential roles in survival and reproduction. However, the molecular basis of these conspicuous colors remains unresolved.

RESULTS: We investigate color morph-enriched Asian vine snakes...

2023-02-23 | MTBLS6927 | MetaboLights
MetabolomicsCardiac untargeted lipidomics in cardiomyocyte-specific SREBP1 knockdown mice

Background: Heart failure with reduced ejection fraction (HFrEF) is characterized by impaired contractility and high mortality. Dysregulation of intracellular ion cycling underlies the decline in cardiac contractility. Modulation of cardiac Na+/H+ and Ca2+ handling is consider...

2026-02-20 | MTBLS13696 | MetaboLights
TranscriptomicsTranscriptomic analysis of differential genetic expression under CosR-knockdown condition compared with wild-type
We perfomed the transcriptomic analysis of differential genetic expression in the CosR-knockdown condition with a DNA microarray. CosR-specific antisense-PNA was used for CosR-knockdown. The results revealed that CosR significantly affected the expression of several genes involved in various cellula...
ORGANISM(S): Campylobacter jejuni 
2013-01-01 | E-GEOD-40201 | biostudies-arrayexpress
ProteomicsmARC1 knockdown protects liver from diet-induced NASH in mouse
Human genetic studies have identified several MARC1 variants as protective against non-alcoholic fatty liver diseases (NAFLD). The MARC1 variants are associated with reduced lipid profiles, liver enzymes, and liver-related mortality. However, the role of mitochondrial amidoxime reducing component 1 ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-04-28 | MSV000091820 | MassIVE
TranscriptomicsGene expression profiling of selenophosphate synthetase 2 knockdown in Drosophila melanogaster
Selenium (Se) is an important trace element for many organisms and is incorporated into selenoproteins as selenocysteine (Sec). In eukaryotes, selenophosphate synthetase SPS2 is essential for Sec biosynthesis. In recent years, genetic disruptions of both Sec biosynthesis genes and selenoprotein gene...
ORGANISM(S): Drosophila melanogaster 
2016-04-06 | E-GEOD-79924 | biostudies-arrayexpress
GenomicsEffect of genetic knockdown Emb on enteric neuronal development in mice
Effect of genetic knockdown Emb on enteric neuronal development in mice
PRJNA1451067 | ENA
GenomicsRNA Sequencing of 16D Prostate Cancer Cell Lines with genetic knockdown of OGDHL
RNA Sequencing of 16D Prostate Cancer Cell Lines with genetic knockdown of OGDHL
PRJNA1268935 | ENA
GenomicsRNA-seq analysis after genetic overexpression or knockdown of TP73 in TL-Om1 cells
RNA-seq analysis after genetic overexpression or knockdown of TP73 in TL-Om1 cells
PRJNA751061 | ENA
ProteomicsHYDIN2 knockdown in NT2 cells analyses by LFQ
Segmental duplications at proximal loci can generate transcriptionally active chimeric pseudogenes (φgenes) by fusing contiguous sequences from two parental genes. These chimeric φgenes often co-opt 5′ regulatory elements for activation and acquire 3′ modifications that enhance transcript stability,...
ORGANISM(S): Homo sapiens (Human) 
2026-05-25 | PXD074698 | Pride
Hydin2 Chimeric pseudogene Lfq proteomics 
GenomicsEffect of genetic knockdown Emb on enteric neural crest cell development in mice.
Effect of genetic knockdown Emb on enteric neural crest cell development in mice.
PRJNA1451175 | ENA
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