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TranscriptomicsDeep sequencing of the murine Igh repertoire reveals complex regulation of non-random V gene rearrangement frequencies (RNA-seq)
A diverse antibody repertoire is formed through the rearrangement of V, D, and J segments at the immunoglobulin heavy chain (Igh) loci. The C57BL/6 murine Igh locus has over 100 functional VH gene segments that can recombine to a rearranged DJH. While the non-random usage of VH genes is well documen...
ORGANISM(S): Mus musculus 
2013-08-05 | E-GEOD-47885 | biostudies-arrayexpress
GenomicsMassive genomic rearrangement acquired in a single catastrophic event during cancer development - samples
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
EGAD00001000002 | EGA
UnknownGenomic Rearrangement Signatures and Clinical Outcomes in High-Grade Serous Ovarian Cancer.
Not available
S-EPMC6054271 | biostudies-literature
GenomicsHigh-throughput capture of cis-rearrangement and trans-rearrangement sequence [LAM-HTGTS]
High-throughput capture of cis-rearrangement and trans-rearrangement sequence [LAM-HTGTS]
PRJNA574913 | ENA
TranscriptomicsComparative genomic hybridization of 5 hominid species, including humans
Given that gene duplication is a major driving force of evolutionary change and the key mechanism underlying the emergence of new genes and biological processes, this study sought to use a novel genome-wide approach to identify genes that have undergone lineage-specific duplications or contractions ...
ORGANISM(S): Homo sapiens 
2013-01-30 | E-SMDB-2855 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of Taeniopyggia guttata (zebra finch) male and female genome copy number analysis.
Comparative genomic hybridsation of genomic DNA from a male and a female zebra finch to the Roche NimbleGen chicken whole genome oligonucleotide array
ORGANISM(S): Taeniopygia guttata 
2009-11-17 | E-TABM-841 | biostudies-arrayexpress
TranscriptomicsGenomic comparison in Vibrio parahaemolyticus strains by comparative genomic hybridization.
Vibrio parahaemolyticus is a Gram-negative marine bacterium. A limited population of the organisms causes acute gastroenteritis in humans. Almost all of the clinical V. parahaemolyticus isolates exhibit a beta-type hemolysis on Wagatsuma agar, known as the Kanagawa phenomenon (KP). KP is induced by ...
ORGANISM(S): Vibrio parahaemolyticus 
2010-05-25 | E-GEOD-10020 | biostudies-arrayexpress
UnknownIdentification of a complex genomic rearrangement in TMPRSS3 by massively parallel sequencing in Chinese cases with prelingual hearing loss.
Not available
S-EPMC6565588 | biostudies-literature
GenomicsLoss of histone demethylase JARID1C triggers genomic instability in cancer.
Chromatin remodelers are recurrently mutated in cancer. Among these, JARID1C, (KDM5C) a histone demethylase, is frequently inactivated in clear cell renal cell carcinoma (ccRCC) patients. How the genetic inactivation of JARID1C leads to cancer remains largely unknown. Here we report that JARID1C bin...
ORGANISM(S): Homo sapiens 
2015-11-09 | E-GEOD-73267 | biostudies-arrayexpress
GenomicsChloroplast DNA rearrangement assay
Chloroplast DNA rearrangement assay
PRJEB41149 | ENA
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