Sort   by:  
 Page size 
MetabolomicsComparative non-targeted LC-MS metabolomic profiling of murine bone marrow-derived macrophages cultured in 2D versus 3D

Macrophages are key drivers of inflammatory and fibrotic diseases and their activation is shaped by interactions in their tissue microenvironment. However, dissecting the processes that drive immunopathology has proved challenging as traditional 2D culture methods fail to capture the complex mole...

2026-06-08 | MTBLS12917 | MetaboLights
MetabolomicsExperimental and computational approaches for deep metabolome annotation with application to the ecotoxicological model organism Daphnia magna

Identifying metabolomes with greater coverage and confidence is a critical step towards interpreting the metabolic basis of human and environmental health. Yet for over two decades the field of metabolomics has been inhibited by limited metabolite identification. To address this, we developed the...

MTBLS2273 | MetaboLights
ProteomicsD-Cysteine impairs tumour growth by inhibiting cysteine desulfurase NFS1
Selective targeting of cancer cells is a major challenge for cancer therapy. Many cancer cells overexpress the cystine/glutamate antiporter xCT/CD98, a transport system that imports L-cystine to strengthen antioxidant defenses, thereby promoting tumour survival and progression. We have exploited thi...
ORGANISM(S): Homo sapiens (Human) 
2025-09-01 | PXD063479 | Pride
Iron-sulfur cluster Iron-sulfur protein biogenesis Iron homeostasis. Cancer Amino acid 
UnknownGentle, fast and effective crystal soaking by acoustic dispensing.
Not available
S-EPMC5349437 | biostudies-literature
ProteomicsDaphnia pulex_Lysine acetylation
Daphnia (Daphnia pulex) is a small planktonic crustacean and a key constituent of aquatic ecosystems. It is commonly used as a model organism for studying environmental toxic challenges. In the past decade, a Daphnia genomic information and proteomic dataset has been developed. This dataset has expa...
ORGANISM(S): Daphnia pulex (Water flea) 
2016-01-05 | PXD002441 | Pride
D. pulex  lysine acetylation  post-translational modification  proteomics 
UnknownToward gentle chokeberry juice production by ultrasound-assisted enzymatic maceration.
Not available
S-EPMC10248796 | biostudies-literature
UnknownMEC-10 and MEC-19 Reduce the Neurotoxicity of the MEC-4(d) DEG/ENaC Channel in Caenorhabditis elegans.
Not available
S-EPMC4825646 | biostudies-literature
ProteomicsSuccinylome analysis reveals the involvement of lysine succinylation in extreme resistance of Deinococcus radiodurans
Increasing evidences showing that succinylation of lysine residue mainly regulates enzymes involved in the carbon metabolism pathway, both in prokaryotic and eukaryotic cells. Deinococcus radiodurans is one of the most radioresistant organisms on earth, which is famous for its robust resistance. A m...
ORGANISM(S): Deinococcus radiodurans 
2021-04-26 | PXD012149 | Pride
Succinylome  succinylation  dna repair  nucleic acid binding  posttranslational modification 
UnknownDrosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation.
Not available
S-EPMC3917554 | biostudies-literature
UnknownOrganelle-specific phase contrast microscopy enables gentle monitoring and analysis of mitochondrial network dynamics.
Not available
S-EPMC8367278 | biostudies-literature
Sort   by:  
 Page size