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ProteomicsLocal depletion of proteoglycans mediates cartilage tissue repair in an ex vivo integration model
Successfully replacing damaged cartilage with tissue-engineered constructs requires integration with the host tissue and could benefit from leveraging the native tissue's intrinsic healing capacity; however, efforts are limited by a poor understanding of how cartilage repairs minor defects. Here, we...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-07-18 | PXD035246 | Pride
Proteoglycan depletion Cartilage repair Catabolic enzyme Tissue engineering 
TranscriptomicsSparse feature selection methods identify unexpected global cellular response to strontium-containing materials
Despite the increasing sophistication of biomaterials design and functional characterization studies, little is known regarding cells' global response to biomaterials. Here, we combined nontargeted holistic biological and physical science techniques to evaluate how simple strontium ion incorporation...
ORGANISM(S): Homo sapiens 
2018-11-25 | E-MTAB-7384 | biostudies-arrayexpress
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