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ProteomicsO-GlcNAcylation promotes Palbociclib resistance in breast cancer by regulating MITF nuclear translocation
Cyclin-dependent kinases 4 and 6 (CDK4/6) are essential drivers of the cell cycle and are also critical for the initiation and progression of diverse malignancies. Pharmacological inhibitors targeting CDK4/6 have demonstrated significant activity against various tumor types such as breast cancer. Ho...
ORGANISM(S): Homo sapiens (Human) 
2024-05-30 | PXD042838 | Pride
Mitf Palbociclib O-glcnac 
ProteomicsO-GlcNAcylation promotes Palbociclib resistance in breast cancer by regulating MITF nuclear translocation
Cyclin-dependent kinases 4 and 6 (CDK4/6) are essential drivers of the cell cycle and are also critical for the initiation and progression of diverse malignancies. Pharmacological inhibitors targeting CDK4/6 have demonstrated significant activity against various tumor types such as breast cancer. Ho...
ORGANISM(S): Homo sapiens (Human) 
2024-05-30 | PXD042763 | Pride
O-glcnacylation Mitf Palbociclib 
UnknownRandomized international phase III trial of ERCC1 and RRM1 expression-based chemotherapy versus gemcitabine/carboplatin in advanced non-small-cell lung cancer.
Not available
S-EPMC3691357 | biostudies-literature
UnknownMaking change last? Exploring the value of sustainability approaches in healthcare: a scoping review
Not available
S-EPMC7556957 | biostudies-literature
UnknownGenomic analysis reveals that immune function genes are strongly linked to clinical outcome in the North Central Cancer Treatment Group n9831 Adjuvant Trastuzumab Trial.
Not available
S-EPMC4334774 | biostudies-literature
MetabolomicsAssessing the impact of nitrogen supplementation in oats across multiple growth locations and years with targeted phenotyping and high-resolution metabolite profiling approaches
Oats (Avena sativa L.) are a healthy food, being high in dietary fibre (e.g. β-glucans), antioxidants, minerals, and vitamins. Understanding the effect of variety and crop management on nutritional quality is important. The response of four oat varieties to increased nitrogen levels was investigated...
2021-04-26 | MTBLS1801 | MetaboLights
UnknownCan patient navigation improve receipt of recommended breast cancer care? Evidence from the National Patient Navigation Research Program.
Not available
S-EPMC4145185 | biostudies-literature
UnknownTrastuzumab plus adjuvant chemotherapy for human epidermal growth factor receptor 2-positive breast cancer: planned joint analysis of overall survival from NSABP B-31 and NCCTG N9831.
Not available
S-EPMC4226805 | biostudies-literature
UnknownO-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer.
Not available
S-EPMC11222436 | biostudies-literature
UnknownSWOG S0221: a phase III trial comparing chemotherapy schedules in high-risk early-stage breast cancer.
Not available
S-EPMC4268253 | biostudies-literature
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