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TranscriptomicsBrain metastasis from lung adenocarcinoma patients
Microarray analysis of 28 brain metastasis samples from lung adenocarcinoma patients. 28 brain metastasis samples: 19 from Marc Ladanyi 9 from William L. Gerald
ORGANISM(S): Homo sapiens 
2010-06-17 | E-GEOD-14108 | biostudies-arrayexpress
MetabolomicsAssessing the impact of nitrogen supplementation in oats across multiple growth locations and years with targeted phenotyping and high-resolution metabolite profiling approaches
Oats (Avena sativa L.) are a healthy food, being high in dietary fibre (e.g. β-glucans), antioxidants, minerals, and vitamins. Understanding the effect of variety and crop management on nutritional quality is important. The response of four oat varieties to increased nitrogen levels was investigated...
2021-04-26 | MTBLS1801 | MetaboLights
TranscriptomicsTranscriptome of mouse erythroid cells (part1) poly(A)+
We report genome-wide maps of transcription in mouse erythroid cells. We used an approach to survey poly(A)+ (mRNA) (GSE26877) and non-polyadenylated RNA poly(A)- (GSE27920) separately. This provides an alternative framework for comprehensive transcriptome profiling in mammalian cells. Two Samples. ...
ORGANISM(S): Mus musculus 
2012-01-30 | E-GEOD-26877 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human LM2 cells transduced with miR-335 expression vector vs. control
the LM2 breast cancer cell line is an in vivo derived line from the MDA-MB-231 parental line. this LM2 line has been transduced either with a short hairpin control or miR-335 expression vector. Experiment Overall Design: the LM2 cell line is transduced either with a short hairpin control vector or ...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9586 | biostudies-arrayexpress
TranscriptomicssiRNA profiling of human steroid-deprived LNCaP cells were transfected with control or ART-27 siRNA to investigate the genome-wide impact of ART-27 loss on androgen-regulated transcription
The androgen receptor (AR) directs diverse biological processes through interaction with coregulators such as androgen receptor trapped clone-27 (ART-27). The impact of ART-27 on genome-wide transcription was examined. The studies indicate that loss of ART-27 enhances expression of many androgen-reg...
ORGANISM(S): Homo sapiens 
2009-06-08 | E-GEOD-14043 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of mRNA expression in prospectively purified human prostate orthotopic xenograft tumor cells with varying S/TFE
Human prostate CWR22 OT-tumor cells were prospectively purified for expression of various stem cell markers (TRA-1-60/CD151/CD166/EpCAM/CD44/α2-Integrin). Unsorted total tumor cells or the additional marker positive cells that do not manifest stem-like characteristics were used as control. All these...
ORGANISM(S): Homo sapiens 
2010-12-06 | E-GEOD-25690 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung cancer cells treated with 5-aza - a genome-wide screen for hypermethylated genes in lung cancer
Abstract; Background: Promoter hypermethylation coupled with loss of heterozygosity at the same locus results in loss of gene function in many tumor cells. The “rules” governing which genes are methylated during the pathogenesis of individual cancers, how specific methylation profiles are init...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5816 | biostudies-arrayexpress
TranscriptomicsMethylation profiling of human NSCLC promoter regions identifies novel methylation markers for multiple malignancies
BACKGROUND: Promoter hypermethylation coupled with loss of heterozygosity at the same locus results in loss of gene function in many tumor cells. The "rules" governing which genes are methylated during the pathogenesis of individual cancers, how specific methylation profiles are initially establishe...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6695 | biostudies-arrayexpress
TranscriptomicsResponse of fresh or frozen peripheral blood mononuclear cells from 1 healthy donor to influenza virus derived peptide stimulation.
CD4 T cell responses are characterized based on a limited number of molecular markers selected from exisiting knowledge. The goal of the experiment was to assess antigenic-peptide specific T-cell responses in vitro without bias using microarrays. PBMCs were isolated from 1 healthy donor. The fresh c...
ORGANISM(S): Homo sapiens 
2016-08-15 | E-GEOD-72375 | biostudies-arrayexpress
TranscriptomicsResponse of peripheral blood mononuclear cells from young (≤ 45 years old) and old (>60 years old) healthy donors to influenza virus derived peptide stimulation.
CD4 T cell responses are characterized based on a limited number of molecular markers selected from exisiting knowledge. The goal of the experiment was to assess antigenic-peptide specific T-cell responses in vitro without bias using microarrays. PBMCs were isolated from 11 young (≤ 45 years old) ...
ORGANISM(S): Homo sapiens 
2016-08-15 | E-GEOD-72374 | biostudies-arrayexpress
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