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OtherComprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells.
Data from ProteomeXchange, PXD ID: PXD001416. File: PBMC_1_con_cyt1-4.mgf. Published as part of J Proteome Res. 2014 Oct 27 . From the Abstract: {{i}} Monitoring proteins involved in regulatory effects may help to improve our understanding of inflammation. We have analyzed proteome alterations indu...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320004830 | GPMDB
Resource Reanalysis 
ProteomicsSelective Arylation of Selenocysteine of Thioredoxin Reductase 1 by an Organogold Compound: Expanding the Tool-Box of Metal-Templated Reactions in Cancer Cells – pull-down
Cyclometalated gold(III) complexes have been reported to template C-S cross-coupling reactions in a biological environment and acting as modifies of cysteine residues. To broaden the scope of organogold complexes for covalent protein post-translational modification in cancer cells, an oxime-containi...
ORGANISM(S): Homo sapiens (Human) 
2025-04-22 | PXD044971 | Pride
Arylation ∙ cancer ∙ chemoproteomics ∙ gold ∙ metals in medicine ∙ selenoprotein ∙ thioredoxin reductase 1 
ProteomicsSelective Arylation of Selenocysteine of Thioredoxin Reductase 1 by an Organogold Compound: Expanding the Tool-Box of Metal-Templated Reactions in Cancer Cells - profiling
Cyclometalated gold(III) complexes have been reported to template C-S cross-coupling reactions in a biological environment and acting as modifies of cysteine residues. To broaden the scope of organogold complexes for covalent protein post-translational modification in cancer cells, an oxime-containi...
ORGANISM(S): Homo sapiens (Human) 
2025-04-22 | PXD044966 | Pride
Arylation ∙ cancer ∙ chemoproteomics ∙ gold ∙ metals in medicine ∙ selenoprotein ∙ thioredoxin reductase 1 
UnknownMesothelioma-associated fibroblasts enhance proliferation and migration of pleural mesothelioma cells via c-Met/PI3K and WNT signaling but do not protect against cisplatin.
Not available
S-EPMC9869633 | biostudies-literature
ProteomicsProteomic and morphologic characterization of ovine macrophage differentiation and polarization – cell lysates
Macrophages play crucial roles in inflammation and tissue homeostasis, exhibiting phenotypic and functional plasticity that enables them to initiate, sustain, or resolve inflammation. To support the evidence-based selection of biomedically relevant preclinical models, this study comprehensively char...
ORGANISM(S): Ovis aries 
2026-01-12 | PXD069059 | Pride
Proteomics Macrophage differentiation Tissue repair Inflammation Sheep 
ProteomicsProteomic and morphologic characterization of ovine macrophage differentiation and polarization - secretomes
Macrophages play crucial roles in inflammation and tissue homeostasis, exhibiting phenotypic and functional plasticity that enables them to initiate, sustain, or resolve inflammation. To support the evidence-based selection of biomedically relevant preclinical models, this study comprehensively char...
ORGANISM(S): Ovis aries 
2026-01-12 | PXD068541 | Pride
Proteomics Macrophage differentiation Tissue repair Inflammation Sheep 
ProteomicsAging-related proteome alterations in B cells may predispose for chronic lymphocytic leukemia - nuclear proteins of JVM-13 cells
Chronic lymphocytic leukemia (CLL), the most common type of leukemia in adults, is still incurable despite the development of novel therapeutic strategies. This reflects the incomplete understanding of the pathophysiology of this disease. In order to get more detailed insights into CLL development, ...
ORGANISM(S): Homo sapiens (Human) 
2017-12-06 | PXD006590 | Pride
Glutaminolysis Chronic lymphocytic leukemia Shotgun proteomics Primary human b lymphocytes Aging Fatty acid beta oxidation Q exactive orbitrap 
ProteomicsAging-related proteome alterations in B cells may predispose for chronic lymphocytic leukemia - nuclear proteins of CLL cells
Chronic lymphocytic leukemia (CLL), the most common type of leukemia in adults, is still incurable despite the development of novel therapeutic strategies. This reflects the incomplete understanding of the pathophysiology of this disease. In order to get more detailed insights into CLL development, ...
ORGANISM(S): Homo sapiens (Human) 
2017-12-06 | PXD006589 | Pride
Glutaminolysis Chronic lymphocytic leukemia Shotgun proteomics Primary human b lymphocytes Aging Fatty acid beta oxidation Q exactive orbitrap 
ProteomicsAging-related proteome alterations in B cells may predispose for chronic lymphocytic leukemia - nuclear proteins of elderly B cells
Chronic lymphocytic leukemia (CLL), the most common type of leukemia in adults, is still incurable despite the development of novel therapeutic strategies. This reflects the incomplete understanding of the pathophysiology of this disease. In order to get more detailed insights into CLL development, ...
ORGANISM(S): Homo sapiens (Human) 
2017-12-05 | PXD006571 | Pride
Glutaminolysis Chronic lymphocytic leukemia Shotgun proteomics Primary human b lymphocytes Aging Fatty acid beta oxidation Q exactive orbitrap 
ProteomicsAging-related proteome alterations in B cells may predispose for chronic lymphocytic leukemia - nuclear proteins of young B cells
Chronic lymphocytic leukemia (CLL), the most common type of leukemia in adults, is still incurable despite the development of novel therapeutic strategies. This reflects the incomplete understanding of the pathophysiology of this disease. In order to get more detailed insights into CLL development, ...
ORGANISM(S): Homo sapiens (Human) 
2017-12-05 | PXD006576 | Pride
Glutaminolysis Chronic lymphocytic leukemia Shotgun proteomics Primary human b lymphocytes Aging Fatty acid beta oxidation Q exactive orbitrap 
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