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ProteomicsProteomics analysis of High-grade glioma tissues showing differential fluorescence following 5-Aminolevulinic acid guided surgery
Targeted treatment of high-grade gliomas (HGGs) is challenging due to intra- and inter-tumoral heterogeneity. Prognosis of these tumors relies largely on the extent of resection. Fluorescence guided surgery using 5-ALA as adjunct has been on the rise in the recent years. However, 5-ALA has been inef...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD039170 | Pride
Deep proteome Protoporphyrin ix 5-aminolevulinic acid Gene set enrichment analysis Heme biosynthesis Lc-ms High-grade gliomas 
ProteomicsMRM for validation of Brain tumor biomarkers
The emergence of omics technologies over the last decade has helped in advancement of research and our understanding of complex diseases like brain cancers. However, barring genomics, no other omics technology has been able to find utility in clinical settings. The recent advancements in mass spectr...
ORGANISM(S): Homo Sapiens 
2021-06-15 | PXD024238 | panorama
ProteomicsOrgan wise targeted mass spectrometric analysis of proteins in Labeo rohita using SRM/MRM approach
In order to analyse the tissue enriched expression of proteins using Selected reaction monitoring approach, a set of 45 proteins were selected. Targeted proteomics data for the selected proteins was acquired for nine different tissues in Labeo rohita including brain, embryo, eye, female gonad, hear...
ORGANISM(S): Labeo Rohita 
2022-01-01 | PXD028017 | panorama
ProteomicsValidation of detected viral and host peptides from COVID-19 nasopharyngeal swab samples
In the current scenario of COVID-19, an assay that can efficiently and specifically detect infection by SARS-COV2 is required. Nasopharyngeal swabs are non-invasive samples and can be conveniently acquired from the population to be screened. In this work, we have validated a few viral and host pepti...
ORGANISM(S): Homo Sapiens Severe Acute Respiratory Syndrome Coronavirus 2 
2021-04-02 | PXD021845 | panorama
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