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TranscriptomicsHybrid Mouse diversity Panel Liver Expression Profile
Novel, systems-based approach to mouse genetics. Expression Profiles from 99 strains of inbred and recombinant inbred mice. Most assayed in triplicate. Two of 288 chips were excluded from the final analysis due to low QC scores.
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-16780 | biostudies-arrayexpress
TranscriptomicsObesity study in transgenic and knockout animals
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-12000 | biostudies-arrayexpress
TranscriptomicsGene networks associated with conditional fear in mice identified using a systems genetics approach
To uncover genetic networks governing the biology of conditional fear, we used a systems genetics approach to analyze a hybrid mouse diversity panel (HMDP) with high mapping resolution. By integrating fear phenotypes, transcript profiling data from hippocampus and striatum and genotype information,...
ORGANISM(S): Mus musculus 
2011-03-15 | E-GEOD-26500 | biostudies-arrayexpress
TranscriptomicsGas7 male transgenic liver expression vs FVB male wildtype control
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-11996 | biostudies-arrayexpress
TranscriptomicsGpx3 male transgenic liver expression vs B6/DBA male wildtype control
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-11997 | biostudies-arrayexpress
TranscriptomicsGyk female heterozygous liver expression vs C57Bl/6J female wildtype control
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-11998 | biostudies-arrayexpress
TranscriptomicsLactb male transgenic liver expression vs FVB male wildtype control
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-11999 | biostudies-arrayexpress
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