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ProteomicsDelivery of MFF through mitochondria-derived vesicles regulates melanosome maturation
Melanosomes are lysosome-associated organelles that produce and accumulate melanin. Their biogenesis begins with the trafficking of melanogenic proteins from the endo-lysosomal system into non-pigmented vacuoles derived from endosomes. Subsequently, melanosome maturation proceeds with the export and...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-25 | PXD051372 | Pride
Mitochondria Mff Melanosome 
ProteomicsPlasma proteome profiling of healthy subjects undergoing bed rest reveals unload-dependent changes linked to muscle atrophy.Plasma proteome profiling of healthy subjects undergoing bed rest reveals unload-dependent changes linked to muscle atrophy.
Inactivity and unloading. induce skeletal muscle atrophy, loss of strength and detrimental metabolic effects. We used mass spectrometry-based proteomics to measure the abundance changes of proteins circulating in the blood plasma of young healthy subject undergoing ten days of continuous bed rest. S...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD032969 | Pride
Bed rest Proteomics Plasma Skeletal muscle Cachexia Atrophy 
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