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ProteomicsPRMT1-mediated methylation of the Large Drosha Complex regulates microRNA biogenesis
MicroRNA (miRNA) biogenesis is a tightly controlled multi-step process operated in the nucleus by the activity of the Large Drosha Complex (LDC). Through high resolution mass spectrometry (MS) analysis we discovered that the LDC is extensively methylated, with 82 distinct methylated sites associated...
ORGANISM(S): Homo sapiens (Human) 
2019-10-23 | PXD011617 | Pride
Prmt1 Large drosha complex Mass spectrometry Microrna Protein methylation 
ProteomicsRNA-host protein interaction analyses reveal additional proteins involved in SARS-CoV-2 RNA biology
SARS-CoV-2 is a positive single-stranded RNA virus which interacts at different stages with the host proteins of infected cells. These interactions are necessary for the host to recognize and block the replication of the virus. But, at the same time, the virus requires host proteins to translate, tr...
ORGANISM(S): Homo sapiens (Human) 
2023-11-14 | PXD034941 | Pride
Ars-cov-2  interactome  host-virus interactions  rbps 
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