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In order to evaluate the impact of PCYOX1 deletion on adipogenesis, we applied a label-free mass spectrometry-based proteomic approach to compare the proteome of 3T3-L1 differentiated for 9 days to adipocytes after PCYOX1 gene silencing. Pcyox1 was silenced using shRNA lentiviral particles. Control ...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD039943 | Pride
Duchenne muscular dystrophy (DMD) is a rare and devastating genetic disorder, whose management is still a major challenge, despite progress in genetic and pharmacological disease-modifying treatments have been made. Mitochondrial dysfunctions contribute to DMD, however, there are no effective mitoch...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD055878 | Pride
We applied a label-free mass spectrometry-based proteomic approach to comprehensively characterize the protein cargo of plasma-derived extracellular vesicles (EVs) in individuals with a diagnosis of hypertrophic cardiomyopathy (HCM) compared with healthy volunteers to explore their potential as a di...
ORGANISM(S): Homo sapiens (Human) 
2026-08-04 | PXD080896 | Pride
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