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TranscriptomicsGlobal Methylation Patterns in Idiopathic Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis (IPF) is a chronic progressive lung disease that affects more than 5 million people worldwide with a steady increase in both incidence and mortality. There is currently no effective therapy and the median survival without transplant is 2-5 years. The etiological factor ...
ORGANISM(S): Homo sapiens 
2012-04-18 | E-GEOD-29895 | biostudies-arrayexpress
TranscriptomicsEnhanced MyoD-Induced Transdifferentiation to a Myogenic Lineage by Fusion to a Potent Transactivation Domain
Synthetic transcription factors can be applied to many areas of biotechnology, medicine, and basic research.  Currently, the most common method for engineering synthetic transcription factors has been based on programmable DNA-binding domains of zinc finger proteins, Transcription Activator-Like Ef...
ORGANISM(S): Homo sapiens 
2014-12-11 | E-GEOD-62448 | biostudies-arrayexpress
TranscriptomicsDistinct gene signatures define pathogen- versus diet-induced atherosclerosis development
The goal of this study was to define gene expression profiles in aortic tissue in response to three pro-atherogenic stimuli at two time points. We identified gene expression profiles induced by oral P.gingivalis (Pg), intranasal C. pneumoniae (Cp), and Western diet (WD) at acute (1 day after last in...
ORGANISM(S): Mus musculus 
2015-01-06 | E-GEOD-60086 | biostudies-arrayexpress
TranscriptomicsArabidopsis transcriptome responses to mitochondrial perturbations
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Arabidopsis thaliana 
2013-01-01 | E-GEOD-29269 | biostudies-arrayexpress
UnknownCommon and rare variant genetic contributions in African Americans with autism.
Not available
S-EPMC12668067 | biostudies-literature
TranscriptomicsInhibition of the mitochondrial TCA cycle by monofluoroacetate in Arabidopsis thaliana
Plant mitochondria signal to the nucleus leading to altered transcription of nuclear genes by a process called mitochondrial retrograde regulation (MRR). MRR is implicated in metabolic homeostasis and responses to stress conditions. Transcriptional consequences on nuclear gene expression of mitochon...
ORGANISM(S): Arabidopsis thaliana 
2013-01-01 | E-GEOD-29268 | biostudies-arrayexpress
TranscriptomicsInhibition of the mitochondrial electron transport chain by antimycin A in Arabidopsis thaliana
Plant mitochondria signal to the nucleus leading to altered transcription of nuclear genes by a process called mitochondrial retrograde regulation (MRR). MRR is implicated in metabolic homeostasis and responses to stress conditions. Transcriptional consequences on nuclear gene expression of mitochon...
ORGANISM(S): Arabidopsis thaliana 
2013-01-01 | E-GEOD-29204 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human children with mental retardation and immediate family members
The cause of mental retardation in one-third to one-half of all affected individuals is unknown. Microscopically-detectable chromosomal abnormalities are the most frequent recognized cause, but gain or loss of chromosomal segments that are too small to be seen by conventional cytogenetic analysis ha...
ORGANISM(S): Homo sapiens 
2008-06-21 | E-GEOD-7226 | biostudies-arrayexpress
UnknownPDBe-KB: collaboratively defining the biological context of structural data.
Not available
S-EPMC8728252 | biostudies-literature
UnknownData sharing to improve concordance in variant interpretation across laboratories: results from the Canadian Open Genetics Repository.
Not available
S-EPMC8523590 | biostudies-literature
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