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ProteomicsMultiplexed, scheduled high resolution sMRM-HR acquisition on full scan MS/MS instruments
Advances in software and high resolution, high mass accuracy mass spectrometers have expanded their functionality beyond traditional data dependent acquisition (DDA) methods. Using a single platform, an orthogonal quadrupole time-of flight (QqTOF) mass spectrometer, the TripleTOF 5600, we have inve...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Escherichia Coli (ncbitaxon:562) Saccharomyces Cerevisiae (ncbitaxon:4932) 
2015-03-10 | MSV000079077 | MassIVE
TranscriptomicsFunctional genomic analysis of the periodic transcriptome in the developing Drosophila wing [Affymetrix]
The eukaryotic cell cycle, driven by both transcriptional and post-translational mechanisms, is the central molecular oscillator underlying tissue growth throughout animals. While genome-wide studies have investigated cell cycle-associated transcription in unicellular systems, global patterns of pe...
ORGANISM(S): Drosophila melanogaster 
2014-03-15 | E-GEOD-54926 | biostudies-arrayexpress
UnknownDevelopment of a Multiplex PCR and Magnetic DNA Capture Assay for Detecting Six Species Pathogens of the Genera Anaplasma and Ehrlichia in Canine, Bovine, Caprine and Ovine Blood Samples from Grenada, West Indies.
Not available
S-EPMC7916465 | biostudies-literature
TranscriptomicsTranscriptional profiling of Drosophila wing pouch following CR32027 RNAi
The eukaryotic cell cycle, driven by both transcriptional and post-translational mechanisms, is the central molecular oscillator underlying tissue growth throughout animals. While genome-wide studies have investigated cell cycle-associated transcription in unicellular systems, global patterns of pe...
ORGANISM(S): Drosophila melanogaster 
2014-03-15 | E-GEOD-54927 | biostudies-arrayexpress
ProteomicsMudPIT analyses of the proteins co-purified with the junction-localized tumor suppressors Scribble (Scrib) and Discs Large (Dlg) by immunoprecipitation from fly embryos
Fly embryos (w1118, Dlg-GFP, or Scrib-GFP) were lysed with lysis buffer (25mM Tris-HCl, 150mM EDTA, 1% NP-40, 5% glycerol, 1mM DTT, 1x protease inhibitor). Debris was removed by centrifugation, and extracts were cleared by incubation with Dynabeads (1 hour). Immunocomplexes were formed by incubation...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
MSV000082907 | MassIVE
TranscriptomicsMechanisms of tentacle morphogenesis in the sea anemone, Nematostella vectensis
Evolution of the capacity to form secondary outgrowths from the principal embryonic axes was a crucial innovation that potentiated the diversification of animal body plans. Nevertheless, precisely how such outgrowths develop in early-branching metazoan species remains poorly understood. To identify...
ORGANISM(S): Nematostella vectensis 
2013-05-01 | E-GEOD-45588 | biostudies-arrayexpress
GenomicsGenome-wide analysis of Yki and Sd localization in imaginal disks of Drosophila eye by ChIP Seq
Throughout Metazoa, developmental processes are controlled by a surprisingly limited number of conserved signaling pathways. Precisely how these signaling cassettes were assembled in early animal evolution remains poorly understood, as do the molecular transitions that potentiated the acquisition o...
ORGANISM(S): Drosophila melanogaster 
2014-03-01 | E-GEOD-54601 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Dll3 and Notch1 homozygous mutant embryos to investigate craniofacial malformations of human birth defects
Mutations in the Notch1 receptor and delta-like 3 (Dll3) ligand cause global disruptions in axial segmental patterning. Genetic interactions between members of the notch pathway have previously been shown to cause patterning defects not observed in single gene disruptions. We examined Dll3-Notch1 ...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-8027 | biostudies-arrayexpress
UnknownEffect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial.
Not available
S-EPMC9170467 | biostudies-literature
UnknownMultivitamins in the prevention of cancer and cardiovascular disease: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial.
Not available
S-EPMC9170475 | biostudies-literature
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