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TranscriptomicsTranscription profiling of human BCR-ABL1-transformed acute lymphoblastic leukemia cells reveals Activation-induced cytidine deaminase acts as a mutator
The Philadelphia chromosome (Ph) encoding the oncogenic BCR-ABL1 kinase defines a subset of ALL with a particularly unfavorable prognosis. Acute lymphoblastic leukemia (ALL) cells are derived from B cell precursors in most cases and typically carry rearranged immunglobulin heavy chain (IGH) variable...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7182 | biostudies-arrayexpress
ProteomicsIndependent human mesenchymal stromal cell-derived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine Graft-versus-Host-Disease model
Extracellular vesicles (EVs) harvested from conditioned media of human mesenchymal stromal cells (MSCs) suppress acute inflammation in various disease models and promote regeneration of damaged tissues. Following successful treatment of an acute steroid-refractory Graft-versus-Host disease (GvHD) pa...
ORGANISM(S): Homo sapiens (Human) 
2023-06-12 | PXD032744 | Pride
Exosomes Graft-versus-host disease Mesenchymal stem cells Extracellular vesicles Heterogeneity Mesenchymal stromal cells 
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