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IMR90 cells were infected with pLNC-RAS:ER (from Jesus Gil lab) with retroviral gene transfer. Infected cells were drug selected G418. The cells were induced either with ethanol as control or with 100nM final conc 4-hydroxytamoxifen (sigma H7904) for ectopic expression of protein We used RNA-Seq to ...
ORGANISM(S): Homo sapiens 
Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors including social communication and stereotypies. In addition to genetic risks, the gut microbiome differs between typically-developing (TD) and ASD individuals, though it remains unclear whether the microbiome contrib...
2019-07-04 | MTBLS726 | MetaboLights
Imipramine, a tricyclic antidepressant, has demonstrated antitumoral properties in various preclinical studies (both in vitro and in vivo), although it is not currently approved for cancer treatment. The aim of this experiment is to investigate the transcriptomic changes associated with imipramine t...
ORGANISM(S): Homo sapiens 
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