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TranscriptomicsPancreatic islet expression profiling in diabetes prone C57BLKS/J mice vs C57BL6/J mice.
C57BLKS/J mice are susceptible to diabetes, because of islet dysfunction, whereas C57BL6/J mice are not. Differences in gene expression between the two strains may account for this sensitivity. Furthermore these differences may only be evident in the hyperstimulated (diabetic or hyperglycemic) state...
ORGANISM(S): Mus musculus 
2008-12-30 | E-GEOD-11257 | biostudies-arrayexpress
ProteomicsSecretome analysis of human A549 Lung cancer cells harboring LKB1 mutations.
STK11 (LKB1) missense somatic mutant isoforms promote tumor growth, motility and inflammation. Elucidating the contribution of somatic mutations to cancer is essential for personalized medicine. STK11 (LKB1) tumor suppressor appears to be inactivated in human cancer, however, somatic missense mutati...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD018041 | Pride
Human  lung cancer  lkb1  lc-msms  secretome 
UnknownEffect of the 2008 economic crisis on oral health in Spain: analysis of serial cross-sectional, population-based health surveys
Not available
S-EPMC9756153 | biostudies-literature
MetabolomicsPathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production

BACKGROUND: Cryopyrin-Associated Periodic Syndrome (CAPS) is an autoinflammatory condition consequence of monoallelic variants in the NLRP3 gene that exacerbate IL-1β production. These variants are gain-of-function, but the exact regulatory mechanism of the NLRP3 CAPS-inflammasom...

2024-01-09 | MTBLS7872 | MetaboLights
UnknownAre We Accurately Predicting Mortality in Renal Cancer? A Systematic Review of Prognostic Models
Not available
S-EPMC12387891 | biostudies-literature
UnknownEffect of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcome: systematic review.
Not available
S-EPMC7276742 | biostudies-literature
UnknownPerformance and Perceptions of Health Care Professionals Using an Immersive Virtual Reality Tool for Home Care Training: Observational Feasibility and Acceptability Study.
Not available
S-EPMC12679075 | biostudies-literature
UnknownA new modular neuroprosthesis suitable for hybrid FES-robot applications and tailored assistance.
Not available
S-EPMC11373245 | biostudies-literature
UnknownGlobal modeling of photochemical reactions in lake water: A comparison between triplet sensitization and direct photolysis.
Not available
S-EPMC11786762 | biostudies-literature
UnknownPsychosocial Nursing Diagnoses of Individuals With Myalgic Encephalomyelitis-Chronic Fatigue Syndrome: A Descriptive Study.
Not available
S-EPMC12041938 | biostudies-literature
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