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TranscriptomicsTranscription profiling of Bos taurus immature oocytes and 8-cell embryos to assess the impact of the loss of sample representation caused by the use of global linear amplification (T7-IVT) during microarray hybridization sample preparation
Assessing the impact of the loss of sample representation caused by the use of global linear amplification (T7-IVT) during microarray hybridization sample preparation.
ORGANISM(S): Bos taurus 
2009-03-25 | E-MEXP-2099 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of the luteinizing hormone surge in bovine granulosa cells (GC) during the pre-ovulation period comparing 2 h pre-LH GC, 6 h post-LH GC and 22 h post-LH GC
The LH surge induces panoply of events that are essential for ovulation and corpus luteum formation. The transcriptional responses to the LH surge of pre-ovulatory granulosa cells are complex and still poorly understood. In the present study, a genome wide bovine oligo array was used to determine ho...
ORGANISM(S): Bos taurus 
2010-10-15 | E-GEOD-23900 | biostudies-arrayexpress
TranscriptomicsEffect of selection on residual feed intake and diet on gene expression in whole blood of pig
Transcriptional profiling in the whole blood of 48 pigs (132 days of age) originated from two lines divergently selected for residual feed intake (RFI) : low-RFI pigs (RFIneg), high-RFI pigs (RFIpl). Both lines were offered isocaloric and isoproteic diets with contrasted energy source and nutrients:...
ORGANISM(S): Sus scrofa 
2016-07-01 | E-GEOD-70838 | biostudies-arrayexpress
TranscriptomicsHybridization of human oocyte cDNA library on the multi-species oocyte array to assess for gene conservation using a temperature stringency criteria
Human oocyte cDNA library was hybridized on a multi-species oocyte array (Bovine, Mouse, Frog) Temperature stringency criteria was used to evaluate the conservation degree of oocyte genes among vertebrates (Bovine, Mouse, Frog) 2 technical replicates on distinct array were made at each pre-determine...
ORGANISM(S): Homo sapiens 
2010-12-15 | E-GEOD-23963 | biostudies-arrayexpress
TranscriptomicsLgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells
Gene inactivation of the orphan G protein-coupled receptor Lgr4, a paralog of the epithelial stem cell marker Lgr5, results in 50% decrease of epithelial cell proliferation and 80% reduction in terminal differentiation of Paneth cells in postnatal mouse intestinal crypts. When cultured ex vivo, Lgr4...
ORGANISM(S): Mus musculus 
2012-03-10 | E-GEOD-27904 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human ductal and lobular breast cancers with familial or Cowden disease history.
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net) | 74 samples on Affymetrix HG-U133 Plus 2.0 GeneChips arrays for 74 patients. 5 samples on CGH CIT v7 | Breast carcinoma is the main malignant tumor occurring in patients wit...
ORGANISM(S): Homo sapiens 
2010-07-29 | E-TABM-854 | biostudies-arrayexpress
TranscriptomicsIdentification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium
Immortal spheroids were generated from fetal mouse intestine using the culture system developed to culture organoids from adult intestinal epithelium. Spheroids are made of a monostratified polarized epithelium displaying a poorly differentiated intestinal phenotype. The proportion of spheroids gene...
ORGANISM(S): Mus musculus 
2014-01-21 | E-GEOD-49803 | biostudies-arrayexpress
GenomicsMELARISK_SNP_MITF_geno
Genotypes at MITF E318K variant
EGAD00000000122 | EGA
GenomicsMELARISK_MITF_geno
Genotypes at MITF E318K variant
EGAD00000000121 | EGA
GenomicsA MITF germline mutation predisposes to melanoma and renal cell carcinoma
Study EGAS00000000048
EGAS00000000048 | EGA
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