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GenomicsGenome-wide chromatin maps of T-cell acute lymphoblastic leukemia (T-ALL) [ChIP-seq]
Here we modeled T-ALL resistance to Notch inhibition, identifying M-bM-^@M-^XpersisterM-bM-^@M-^Y cells that readily expand in the presence of gamma secretase inhibitor (GSI) and the absence of Notch signaling. Rare persister cells are already present in naM-CM-/ve T-ALL populations, and the reversi...
ORGANISM(S): Homo sapiens 
2014-03-01 | E-GEOD-54379 | biostudies-arrayexpress
UnknownLiver lymphatic anatomy and role in systemic lymphatic disease.
Not available
S-EPMC8660706 | biostudies-literature
UnknownStandard 12 month dialectical behaviour therapy for adults with borderline personality disorder in a public community mental health setting.
Not available
S-EPMC5610433 | biostudies-literature
TranscriptomicsHigh-resolution copy number analysis of medulloblastoma
We used high-resolution SNP genotyping to identify regions of genomic gain and loss in the genome of 212 medulloblastomas, a malignant pediatric brain tumor. Focal amplifications of fifteen known oncogenes and focal deletions of twenty known tumor suppressor genes (TSG) were revealed, most not prev...
ORGANISM(S): Homo sapiens 
2010-04-06 | E-GEOD-14437 | biostudies-arrayexpress
UnknownSocioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization.
Not available
S-EPMC10901805 | biostudies-literature
UnknownViral and host mediators of non-suppressible HIV-1 viremia.
Not available
S-EPMC10719098 | biostudies-literature
UnknownThe relationship between body mass index and cardiopulmonary exercise testing in chronic systolic heart failure.
Not available
S-EPMC2762950 | biostudies-literature
UnknownSevere neurocognitive and growth disorders due to variation in THOC2, an essential component of nuclear mRNA export machinery.
Not available
S-EPMC6481655 | biostudies-literature
TranscriptomicsTranscription profiling of human androgen-dependent and androgen-independent primary prostate cancer tumors
Affymetrix U133A comparison of two groups (10 samples each): untreated (androgen-dependent) primary prostate cancer (Gleasons 5-9) and androgen-independent primary prostate cancer. All samples were microdissected for tumor cells only.
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2443 | biostudies-arrayexpress
ProteomicsMetabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | MassIVE
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