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UnknownHistone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State.
Not available
S-EPMC7104854 | biostudies-literature
UnknownOptimization of Cyclophilin B-Targeted Tri-vector Inhibitors for Novel MASH Treatments.
Not available
S-EPMC11956012 | biostudies-literature
Genomicsena-DATASET-MGH2-10-11-2015-05:01:11:768-248 - samples
Whole genome sequences of ACC primagrafts, Histone modification maps and transcription factor binding maps for ACC primagrafts and primary tumors. Processed ChIP-seq data is available on GEO under accession number GSE76465.
EGAD00001001662 | EGA
GenomicsGenetic and epigenetic characterization of adenoid cystic carcinoma
Translocation events are frequent in cancer and may create chimeric fusions or regulatory rearrangements that drive oncogene overexpression. Although regulatory rearrangements are increasingly recognized in hematopoietic and even solid tumors, the underlying mechanisms remain obscure. Here we identi...
EGAS00001001457 | EGA
GenomicsDAC for ACC Study
Data Access Committee EGAC00001000376
EGAC00001000376 | EGA
UnknownGender, blood pressure, and cardiovascular and renal outcomes in adults with hypertension from the Systolic Blood Pressure Intervention Trial.
Not available
S-EPMC7199892 | biostudies-literature
TranscriptomicsTranscription profiling of human androgen-dependent and androgen-independent primary prostate cancer tumors
Affymetrix U133A comparison of two groups (10 samples each): untreated (androgen-dependent) primary prostate cancer (Gleasons 5-9) and androgen-independent primary prostate cancer. All samples were microdissected for tumor cells only.
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2443 | biostudies-arrayexpress
UnknownTherapeutic strategies for diffuse midline glioma from high-throughput combination drug screening.
Not available
S-EPMC7132630 | biostudies-literature
TranscriptomicsHigh-resolution copy number analysis of medulloblastoma
We used high-resolution SNP genotyping to identify regions of genomic gain and loss in the genome of 212 medulloblastomas, a malignant pediatric brain tumor. Focal amplifications of fifteen known oncogenes and focal deletions of twenty known tumor suppressor genes (TSG) were revealed, most not prev...
ORGANISM(S): Homo sapiens 
2010-04-06 | E-GEOD-14437 | biostudies-arrayexpress
ProteomicsMetabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | MassIVE
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