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TranscriptomicsTranscription profiling of human breast cancers to define clinically distinct molecular subtypes in estrogen receptor positive breast carcinomas using genomic grade
Purpose: A number of microarray studies have reported distinct molecular profiles of breast cancers (BC): basal-like, ErbB2-like and two to three luminal-like subtypes. These were associated with different clinical outcomes. However, although the basal and the ErbB2 subtypes are repeatedly recognize...
ORGANISM(S): Homo sapiens 
2008-06-20 | E-GEOD-6532 | biostudies-arrayexpress
TranscriptomicsGene profiling of v-Src transformed primary chicken cells
Cell transformation by the Src tyrosine kinase is characterized by extensive changes in gene expression. To describe these changes, investigators have relied extensively on the study of immortalized rodent cell lines or heterogeneous tumor samples that limit the identification of differentially exp...
ORGANISM(S): Gallus gallus 
2010-02-21 | E-GEOD-14489 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of GFP+ cells isolated from developing 24 hpf mnx1:GFP zebrafish embryos
In this study, we performed single-cell RNA-sequencing (scRNA-seq) on 24 hours post-fertilization (hpf) mnx1:GFP zebrafish embryos to characterize the transcriptional diversity of developing spinal motor neurons. Our goal was to identify molecularly distinct subtypes within the motor neuron populati...
ORGANISM(S): Danio rerio 
2025-11-11 | E-MTAB-15160 | biostudies-arrayexpress
TranscriptomicssnRNA-seq in adult mouse hypothalamus to identify genes responding to thyroid hormone
The study compared two groups of mice first treated to become hypothyroid. The hypothalamus samples collected from each group of mice were pooled (n=4) and nuclei were sorted to prepare two libraries: one group was treated by thyroid hormones to restore normal TH levels, and the other group was left...
ORGANISM(S): Mus musculus 
2025-10-28 | E-MTAB-14810 | biostudies-arrayexpress
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